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Chemical Structure| 13115-43-0 Chemical Structure| 13115-43-0

Structure of 13115-43-0

Chemical Structure| 13115-43-0

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Product Details of [ 13115-43-0 ]

CAS No. :13115-43-0
Formula : C7H7NO2
M.W : 137.14
SMILES Code : O=C(O)CC1=NC=CC=C1
MDL No. :MFCD03412533

Safety of [ 13115-43-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 13115-43-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 13115-43-0 ]

[ 13115-43-0 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 13115-43-0 ]
  • [ 6972-82-3 ]
  • 3-methyl-8-(pyridin-2-ylmethyl)-1H-purine-2,6(3H,7H)-dione [ No CAS ]
YieldReaction ConditionsOperation in experiment
To the suspension of 5,6-diamino-1-methylpyrimidine-2,4(1H,31])-dione (1.0 g,6.40 mmol), 2-(pyridin-2-yl)acetic acid (1.17 g, 6.72 mmol) and DIEA (2.48 g, 19.2 mmol) in DMF (20 mL) was added HATU (2.56 g, 6.72 mmol) and the mixture was stirred for 16h at 25 °C. The precipitate was collected. The solid and NaOH aq. (10 mL, 3M) in EtOH (20 mL) were heated to reflux for 3h. The reaction mixture was cooled to 28 °C and organic solvent was removed. The mixture was neutralized with concentrated HC1 to pH = 89. The precipitate was collected and dried in vacuo to afford the product; ESI: m/z 258.1 (M+H)+
  • 2
  • [ 13115-43-0 ]
  • [ 6972-82-3 ]
  • 3-methyl-8-picolinoyl-1H-purine-2,6(3H,7H)-dione [ No CAS ]
 

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[ 13115-43-0 ]

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A263007 [16179-97-8]

2-(Pyridin-2-yl)acetic acid hydrochloride

Reason: Free-salt