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Chemical Structure| 13162-05-5 Chemical Structure| 13162-05-5

Structure of 13162-05-5

Chemical Structure| 13162-05-5

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Product Details of [ 13162-05-5 ]

CAS No. :13162-05-5
Formula : C3H5NO
M.W : 71.08
SMILES Code : O=CNC=C
MDL No. :MFCD00081206
InChI Key :ZQXSMRAEXCEDJD-UHFFFAOYSA-N
Pubchem ID :83191

Safety of [ 13162-05-5 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H315-H318-H335-H351-H360
Precautionary Statements:P201-P280-P301+P312+P330-P305+P351+P338+P310-P308+P313
Class:6.1
UN#:2810
Packing Group:

Application In Synthesis of [ 13162-05-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 13162-05-5 ]

[ 13162-05-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 13162-05-5 ]
  • [ 103291-07-2 ]
  • N-[(E)-2-(4-fluoro-3-methoxyphenyl)vinyl]formamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
1.68 g With tris-(dibenzylideneacetone)dipalladium(0); N-Methyldicyclohexylamine; tri tert-butylphosphoniumtetrafluoroborate; In 1,4-dioxane;Inert atmosphere; In an argon gas atmosphere, tris(dibenzylideneacetone)dipalladium (0) (558 mg) and tri-tert-butylphosphonium tetrafluoroborate (354 mg) were added to a mixed liquid of <strong>[103291-07-2]4-bromo-1-fluoro-2-methoxybenzene</strong> (5.0 g), N-vinylformamide (2.6 g), N,N-dicyclohexylmethylamine (6.67 g), and dioxane (50 mL), followed by stirring for 16 hours at an oil temperature of 60 C. and cooling to room temperature. The reaction liquid was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (hexane/ethyl acetate), thereby obtaining N-[(E)-2-(4-fluoro-3-methoxyphenyl)vinyl]formamide (1.68 g).
 

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