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Chemical Structure| 132291-95-3 Chemical Structure| 132291-95-3

Structure of 132291-95-3

Chemical Structure| 132291-95-3

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Product Details of [ 132291-95-3 ]

CAS No. :132291-95-3
Formula : C7H14O4S
M.W : 194.25
SMILES Code : CS(=O)(OCC1CCOCC1)=O
MDL No. :MFCD18785628

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Application In Synthesis of [ 132291-95-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 132291-95-3 ]

[ 132291-95-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 35344-95-7 ]
  • [ 132291-95-3 ]
  • 1-(tetrahydropyran-4-ylmethyl)-1H-pyrazole-4-carbaldehyde [ No CAS ]
YieldReaction ConditionsOperation in experiment
48% With caesium carbonate; In N,N-dimethyl-formamide; at 80℃; for 16h; To the stirred solution of lH-<strong>[35344-95-7]pyrazole-4-carbaldehyde</strong> 10-4 (133.97 mg, 1.39 mmol) and tetrahydropyran-4-ylmethyl methanesulfonate 10-3 (325 mg, 1.67 mmol) in DMF ( 10 raL) was added CS2CO3 (2.34 g, 2.79 mmol). The reaction was heated at 80C for 16 hours and then cooled to room temperature, diluted with ethyl acetate, washed with water, brine, dried over sodium sulfate and concentrated under reduced pressure to afford l-(tetrahydropyran-4- ylmethyl)<strong>[35344-95-7]pyrazole-4-carbaldehyde</strong> 10-5 (130 mg, 669.31 umol, 48.00% yield) as gum. 1H NMR (400 MHz, DMSO-d6) 69.87 (s, I l f ), 8.45 (s, 1 1 1 ), 7.99 (s, 1H), 4.08 (d, J = 7.16, 2H), 3.82 (dd, J = 14.16, 2.92 Hz, 21 1 ). 3.27-3.21 (m, 21 1), 2. 10-2.04 (m, H i), 1.39-1.34 (m, 21 1 ). 1.27-1.17 (m, 2H).
 

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