Home Cart Sign in  
Chemical Structure| 13328-85-3 Chemical Structure| 13328-85-3

Structure of 13328-85-3

Chemical Structure| 13328-85-3

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 13328-85-3 ]

CAS No. :13328-85-3
Formula : C10H10O3
M.W : 178.18
SMILES Code : O=C(C1C2=C(C=CC=C2)CCO1)O
MDL No. :MFCD00457636

Safety of [ 13328-85-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Application In Synthesis of [ 13328-85-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 13328-85-3 ]

[ 13328-85-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 13328-85-3 ]
  • [ 5497-76-7 ]
  • [ 543-27-1 ]
  • DL-Isochroman-1-carbonyl-L-proline t-butyl ester [ No CAS ]
YieldReaction ConditionsOperation in experiment
With 4-methyl-morpholine; triethylamine; In ethyl acetate; N,N-dimethyl-formamide; Step B DL-Isochroman-1-carbonyl-L-proline t-butyl ester 4.45 g (25 mmole) of DL-isochroman-1-carboxylic acid (Example 1, Step A) and 2.75 ml (25 mmole) of N-methylmorpholine are dissolved in 20 ml of dimethyl formamide. The solution is cooled to -15 C., then at this temperature and at stirring, first 3.3 ml of isobutyl chloroformate, then, after 10 minutes, the solution or suspension of 5.2 g (25 mmole) of L-proline t-butyl ester hydrochloride and 3.5 ml of triethylamine in 25 ml of dimethyl formamide, cooled to -15 C., are added. Stirring is continued for 2 hours, then the reaction mixture is filtered and evaporated at 15-20 millibar from a water bath at about 40 C. The residue is dissolved in about 30 ml of ethyl acetate and the solution are extracted with 3*20 ml of 0.25M sulfuric acid, water, 5% sodium hydrogen carbonate, again with water, dried over sodium sulfate and evaporated at 20-25 millibar from a water bath of about 40 C. The residue-DL-isochroman-1-carbonyl-L-proline t-butyl ester--is an oily product. ?Rf (7)=0.72 and[0.75].
 

Historical Records

Technical Information

Categories