Home Cart Sign in  
Chemical Structure| 1338378-32-7 Chemical Structure| 1338378-32-7

Structure of 1338378-32-7

Chemical Structure| 1338378-32-7

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1338378-32-7 ]

CAS No. :1338378-32-7
Formula : C6H9IN2O
M.W : 252.05
SMILES Code : CC1=C(I)C(OCC)=NN1

Safety of [ 1338378-32-7 ]

Application In Synthesis of [ 1338378-32-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1338378-32-7 ]

[ 1338378-32-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 1034467-80-5 ]
  • [ 1338378-32-7 ]
  • 5-cyclopropyl-2-(3-ethoxy-4-iodo-5-methyl-1H-pyrazol-1-yl)-pyridine [ No CAS ]
  • 5-cyclopropyl-2-(3-ethoxy-5-methyl-1H-pyrazol-1-yl)pyridine [ No CAS ]
  • 2
  • [ 1034467-80-5 ]
  • [ 1338378-32-7 ]
  • 5-cyclopropyl-2-(3-ethoxy-4-iodo-5-methyl-1H-pyrazol-1-yl)-pyridine [ No CAS ]
YieldReaction ConditionsOperation in experiment
13% With caesium carbonate; In acetonitrile; at 180℃; for 12h;Microwave irradiation; In a 20 mL Biotage tube, 3-ethoxy-4 odo-5-methyl-lH-pyrazole (1.53 g, 6.07 mmol), cesium carbonate (2.2 g, 6.98 mmol and 5-cyclopropyl-2-fiuoropyridine (intermediate 50) (0.87 g, 6.37 mmol) were dispersed in acetonitrile (14 mL, dried over 4A molecular sieves). This was heated at 180 C for 12 hours in the microwave oven. The resulting suspension was adsorbed over silica gel and purified by a chromatography over silica gel (cyclohexane- dichlorom ethane from 97.5/2.5 to 96.5/3.5) to yield 5-cyclopropyl-2-(3-ethoxy-4-iodo-5- methyl-lH-pyrazol-l-yl)pyridine (0.3 g, 13 %) as a solid. (CDCI3): 0.73 (m, 2H); 1.03 (m, 2H); 1.45 (t, 3H, J = 7,2); 1.92 (m, 1H); 2.66 (s, 3H); 4.36 (q, 2H, J = 7.2); 7.39 (dd, 1H, J = 2.4 and 8.5); 7.62 (d, 1H, J = 8.5); 8.20 (d, 1H, J = 2.4). 13C (CDC13): 8.8; 12.6; 14.7; 15.2; 52.8; 65.0; 114.7; 135.1 ; 136.3; 143.0; 145.5; 151.3; 162.4. HRMS: Calc. for Cl4Hi6IN30 + H: 370.0416; Found: 370.0441. 53
 

Historical Records

Technical Information

Categories