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[ CAS No. 1340334-65-7 ]

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2D
Chemical Structure| 1340334-65-7
Chemical Structure| 1340334-65-7
Structure of 1340334-65-7 *Storage: {[proInfo.prStorage]}

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Alternatived Products of [ 1340334-65-7 ]

Product Details of [ 1340334-65-7 ]

CAS No. :1340334-65-7MDL No. :MFCD18861043
Formula : C12H18N2O Boiling Point : -
Linear Structure Formula :-InChI Key :-
M.W :206.28Pubchem ID :-
Synonyms :

Computed Properties of [ 1340334-65-7 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 1340334-65-7 ]

Signal Word:Class:
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Application In Synthesis of [ 1340334-65-7 ]

  • Downstream synthetic route of [ 1340334-65-7 ]

[ 1340334-65-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 110-89-4 ]
  • [ 174913-09-8 ]
  • [ 1340334-65-7 ]
  • 2
  • [ 76661-24-0 ]
  • [ 1340334-65-7 ]
  • 5-chloro-N-(2-methoxy-4-(piperidin-1-yl)phenyl)-4-(3-nitrophenoxy)pyrimidin-2-amine [ No CAS ]
YieldReaction ConditionsOperation in experiment
68.4% With trifluoroacetic acid; In iso-butanol; at 100℃; General procedure: To a solution of 3a-r (1.50 mmol, 1 eq) and 6a-b (1.50 mmol, 1eq) in 2-BuOH (8 mL) were added TFA (2 mL). The slurrywas heatedto 100 C for 2e3 h. The reaction mixture was allowed to cool toroom temperature and was neutralized with a saturated aqueoussodium bicarbonate solution. The mixture was then extracted withethyl acetate (50 mL) three times. The crude was purified by flashchromatography with 25:1 (v/v) dichloromethane - methanol.
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