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Chemical Structure| 134080-67-4 Chemical Structure| 134080-67-4

Structure of 134080-67-4

Chemical Structure| 134080-67-4

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Product Details of [ 134080-67-4 ]

CAS No. :134080-67-4
Formula : C25H16I4
M.W : 824.01
SMILES Code : IC1=CC=C(C(C2=CC=C(I)C=C2)(C3=CC=C(I)C=C3)C4=CC=C(I)C=C4)C=C1
MDL No. :MFCD30478578
InChI Key :GGQCFEVXYDVISX-UHFFFAOYSA-N
Pubchem ID :6422750

Safety of [ 134080-67-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of [ 134080-67-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 134080-67-4 ]

[ 134080-67-4 ] Synthesis Path-Downstream   1~3

  • 2
  • [ 2914-69-4 ]
  • [ 134080-67-4 ]
  • [ 1287732-91-5 ]
  • 3
  • [ 134080-67-4 ]
  • [ 1066-54-2 ]
  • [ 177991-01-4 ]
YieldReaction ConditionsOperation in experiment
72% With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In N,N-dimethyl-formamide; at 35℃; for 15h;Inert atmosphere; In a 500 mL three-necked round-bottomed flask was added tetrakis(4-iodophenyl)methane (17; 10.86 g, 13.19 mmol), PdCl2(PPh3)2 (1.85 g, 2.63 mmol), CuI (501 mg, 2.63 mmol), ethynyltrimethylsilane (2; 18.6 mL, 131.90 mmol), anhyd DMF (180 mL), and Et3N (20 mL) under N2 atmosphere. The reaction mixture was stirred for 15 h at 35 C, after this time the mixture was filtered and the filter cake was saved. The filtrate was diluted with Et2O (200 mL), washed with aq 10% HCl (100 mL), followed by H2O (2 200 mL) and brine (3 200 mL). The organic phase was dried (anhyd Na2SO4) and concentrated. The crude material was purified by column chromatography (PE/CH2Cl2 0:1) to give the tetrakis[4-(trimethylsilylethynyl)phenyl]methane, which was combined with the filter cake; yield: 7.5 g (80%); pale yellow solid. 1H NMR (300 MHz, CDCl3): = 7.34-7.31 (d, J = 8.4 Hz, 8 H), 7.05-7.02 (d, J = 8.4 Hz, 8 H), 0.23 (s, 36 H).21 In a 500 mL one-neck round bottom flask a mixture of tetrakis[4-(trimethylsilylethynyl)phenyl]methane (7.5 g, 10.65 mmol), aq 1 N NaOH (85 mL), and THF (200 mL) was stirred for 1 h at RT. The mixture was concentrated to remove the THF and extracted with CH2Cl2 (200 mL). The organic phase was washed with H2O (100 mL) and brine (100 mL). The organic layer was dried (anhyd Na2SO4) and con-This document was downloaded for personal use only.The resulting residue was purified by column chromatography (PE/toluene 15:1) to afford 18; yield: 3.23 g (72%); pale yellow solid. 1H NMR (300 MHz, CDCl3): = 7.40-7.37 (d, J = 8.4 Hz, 8 H), 7.13-7.10 (d, J = 8.4 Hz, 8 H), 3.06 (s, 4 H). 13C NMR (100 MHz, CDCl3): = 146.2, 131.6, 130.7, 120.2, 83.1, 77.6, 64.7.21
 

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