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Chemical Structure| 1346133-39-8 Chemical Structure| 1346133-39-8

Structure of 1346133-39-8

Chemical Structure| 1346133-39-8

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Product Details of [ 1346133-39-8 ]

CAS No. :1346133-39-8
Formula : C20H19N5O2
M.W : 361.40
SMILES Code : CN1N=CC(C2=NC3=CC(NC4=CC(OC)=CC(OC)=C4)=CC=C3N=C2)=C1
MDL No. :N/A

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Application In Synthesis of [ 1346133-39-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1346133-39-8 ]

[ 1346133-39-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 1346133-39-8 ]
  • [ 6306-61-2 ]
  • [ 1346242-81-6 ]
YieldReaction ConditionsOperation in experiment
Intermediate 3 (20. Og; 55.3mmol), then tetra-N-butylammonium bromide (9.06g;27.7mmol) were added at 2C under inert atmosphere to a solution of potassium hydroxide (46.6g; 830mmol) in THF (387ml_) and water (6ml_). The reaction was stirred at room temperature for 2 hours before portionwise addition of N-(2-chloroethyl)-2- propanamine HCI (CAS[6306-61 -2]), and then at 50C upon complete conversion. Water was added, layers were separated and the organic layer concentrated, taken up in DCM/water, neutralized with HCI to neutral pH. Organic layer was washed with water, dried (MgS04), filtered and evaporated till dryness to give 26.6g of compound 4.
  • 2
  • [ 1346133-39-8 ]
  • [ 1346242-81-6 ]
 

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