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Chemical Structure| 1346245-10-0 Chemical Structure| 1346245-10-0

Structure of 1346245-10-0

Chemical Structure| 1346245-10-0

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Product Details of [ 1346245-10-0 ]

CAS No. :1346245-10-0
Formula : C23H25N5O5S
M.W : 483.54
SMILES Code : CS(=O)(OCCN(C1=CC(OC)=CC(OC)=C1)C2=CC=C3N=CC(C4=CN(C)N=C4)=NC3=C2)=O

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Application In Synthesis of [ 1346245-10-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1346245-10-0 ]

[ 1346245-10-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1346245-10-0 ]
  • [ 75-31-0 ]
  • [ 1346242-81-6 ]
YieldReaction ConditionsOperation in experiment
86.5% In acetonitrile; at 100℃; for 18.0h;sealed vessel;Product distribution / selectivity; A mixture of intermediate 10 (322g; 666mmol) and 2-propanamine (196.8g; 3.3mol) in acetonitrile (2.66L) was heated at 100C in a sealed vessel for 18 hours. The reaction mixture was cooled to room temperature and concentrated to -30% of its initial volume. Water (1 .5L), 2-methyltetrahydrofurane (2.5L) and NaHC03 (50g) were added. The layers were separated, the organic layer was washed with a solution made of 50g of NaHC03 in water (1 L), dried (MgS04), filtered over silica gel and evaporated till dryness. The residue was crystallized from 2-propanol. The precipitate was filtered off, dried in vacuum to provide 257.2g (86.5%) of compound 4.
 

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