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Chemical Structure| 1352609-91-6 Chemical Structure| 1352609-91-6

Structure of 1352609-91-6

Chemical Structure| 1352609-91-6

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Product Details of [ 1352609-91-6 ]

CAS No. :1352609-91-6
Formula : C16H12N6O
M.W : 304.31
SMILES Code : O=CC1=NC(C2=CN3C(C=C2)=NC=N3)=C(C4=NC(C)=CC=C4)N1
MDL No. :MFCD28506210
InChI Key :ZNZIOKJZCOFDAB-UHFFFAOYSA-N
Pubchem ID :86660660

Safety of [ 1352609-91-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 1352609-91-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1352609-91-6 ]

[ 1352609-91-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1352609-91-6 ]
  • [ 6299-67-8 ]
  • C24H21N7O2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With acetic acid; In 1,2-dichloro-ethane; at 120℃; for 2h;Inert atmosphere; Sealed tube; General procedure: To a stirred solution of 11 (13.14 mmol) in 1,2-dichloroethane (240 mL) were added appropriate substituted anilines (19.71 mmol) and AcOH (13.14 mmol), and the mixture was heated to reflux for 2 h under nitrogen atmosphere. The reaction mixture was cooled to 0 C, and MeOH (60 mL) and THF (20 mL) were added. To it, (AcO)3BHNa (26.20 mmol) or NaBH4 (52.56 mmol) was added portionwise, and then the reaction mixture was allowed to warm to room temperature and stirred for an additional 3 h. The pH of the reaction mixture was adjusted to 7-8 at 0 C with 1 NHCl, and then the organic layer was separated. The aqueous layer was extracted with CH2Cl2 (2× 300 mL). The combined organic layers was washed with brine (300 mL) and dried over anhydrous Na2SO4, filtered, and evaporated to dryness under reduced pressure. The residue was purified by MPLC on silica gel to afford the titled compounds as a solid.
 

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