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Chemical Structure| 1374771-55-7 Chemical Structure| 1374771-55-7

Structure of 1374771-55-7

Chemical Structure| 1374771-55-7

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Product Details of [ 1374771-55-7 ]

CAS No. :1374771-55-7
Formula : C10H11ClN2
M.W : 194.66
SMILES Code : CC(C1=CC=C2C(NC(Cl)=N2)=C1)C

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* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1374771-55-7 ]

[ 1374771-55-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 256518-97-5 ]
  • [ 80041-89-0 ]
  • [ 1374771-55-7 ]
YieldReaction ConditionsOperation in experiment
78% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In ethanol; water; toluene; at 120℃; for 3h;Inert atmosphere; Under a nitrogen atmosphere, 2-chloro-6-iodobenzimidazole (2.34 g, 8.4 mmol), <strong>[80041-89-0]isopropylboronic acid</strong> (0.83 g, 9.4 mmol), tetrakistriphenylphosphine palladium (0.09 g, 0.08 mmol) were added to the reaction vessel. ), potassium carbonate (3.48 g, 25.2 mmol), toluene 60 mL, ethanol 20 mL, and distilled water 20 mL, and stirred at 120 ° C for 3 h. After the end of reaction is stopped with distilled water, extracted with ethyl acetate, the organic layer was dried over MgSO4, the solvent was removed by distillation under reduced pressure, to give after compound 78-2 (1.28g, 78percent) was purified by silica gel column chromatography.
 

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