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Chemical Structure| 1383973-47-4 Chemical Structure| 1383973-47-4

Structure of 1383973-47-4

Chemical Structure| 1383973-47-4

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Product Details of [ 1383973-47-4 ]

CAS No. :1383973-47-4
Formula : C11H19NO2
M.W : 197.27
SMILES Code : O=C(C1(C2)CCCC2(N)CC1)OCC

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Application In Synthesis of [ 1383973-47-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1383973-47-4 ]

[ 1383973-47-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5521-61-9 ]
  • [ 1383973-47-4 ]
  • [ 1383973-48-5 ]
YieldReaction ConditionsOperation in experiment
75% With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In dichloromethane; at 18 - 25℃; for 2h;Inert atmosphere; Step 5: 5-|(6-Meth l-p razine-2-carbonyl)-amino|-bicyclo|3.2.1joctane-l-carboxylic acid ethyl ester5-Amino-bicyclo[3.2.1 ]octane- l -carboxylic acid ethyl ester (0.5 g, 2.53 mmol) was dissolved in methylene chloride (10.0 mL, 156 mmol). 6-Methylpyrazine-2-carboxylic acid (0.35 g, 2.53 mmol), benzotriazol- 1 -yloxytris(dimethylamino)phosphonium hexafluorophosphate ( .12 g, 2.53 mmol) and triethylamine (0.71 mL. 5.07 mmol) in methylene chloride (10.0 mL, 156 mmol) were added. The mixture was stirred at rt for 2 hours. The mixture was concentrated under reduced pressure. The resulting residue was purified on the Co b FI sh J system (hexane/ethyl acetate: 100/0 to 30/70 in 8 min, then hexane/ethyl acetate: 30/70) to afford 0.60 g (75percent) of the desired product. ESI-MS m/z: 3 18 (M + H)+
 

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