Home Cart Sign in  
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 13893-53-3 Chemical Structure| 13893-53-3

Structure of AC-94149
CAS No.: 13893-53-3

Chemical Structure| 13893-53-3

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 13893-53-3 ]

CAS No. :13893-53-3
Formula : C6H12N2
M.W : 112.17
SMILES Code : CC(C(C)C)(C#N)N
MDL No. :MFCD00661864
InChI Key :CAOHBROWLMCZRP-UHFFFAOYSA-N
Pubchem ID :94355

Safety of [ 13893-53-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H310-H315-H319-H335-H400
Precautionary Statements:P261-P262-P264-P270-P271-P273-P280-P302+P352-P304+P340-P305+P351+P338-P310-P330-P332+P313-P337+P313-P361-P391-P403+P233-P405-P501
Class:6.1
UN#:2810
Packing Group:

Application In Synthesis of [ 13893-53-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 13893-53-3 ]

[ 13893-53-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 13893-53-3 ]
  • [ 40963-14-2 ]
YieldReaction ConditionsOperation in experiment
Similarly, hydrolysis of (+)-2-amino-2,3.-dimethylbutyronitrile with sulfuric acid yields (-)-2-amino-2,3-dimethylbutyramide, mp 81-82 C., [alpha]D25 =-57.14 (c =0.0654 g/ml THF); and hydrolysis of (+-)2-amino-2,3-dimethylbutyronitrile with sulfuric acid yields (+-)-2-amino2,3dimethylbutyramide, mp 74.5-76 C.
With sulfuric acid; ammonia; In dichloromethane; EXAMPLE 4 Preparation of (+)-2-amino-2,3-dimethylbutyramide A solution of 3.0 g of (-)-2-amino-2,3-dimethylbutyronitrile, [alpha]D =-6.71 (c=0.03307 g/ml THF) in 10 ml methylene chloride is added with stirring at 80 C. to 13.95 g of concentrated sulfuric acid. The solution is heated for one hour, allowed to cool and 14 g of ice is added. Next, 27 ml of concentrated ammonia is added while cooling. The resulting solution is extracted with methylene chloride (5*25 ml). The combined extracts are dried and evaporated to dryness to afford 3.23 g of title product, mp 81-83 C., [alpha]D =+53.04 (c =0.0313 g/ml THF).
With sulfuric acid; ammonia; In ice-acetone; EXAMPLE 2 (Reference) Preparation of 2-amino-2,3-dimethylbutyramide Concentrated sulfuric acid (29.7 ml) is cooled with stirring in an ice-acetone cooling bath. To the acid is added 11.8 g (011 mol) (-)-2-amino-2,3-dimethylbutyronitrile with [alpha] [25/D ] = -7.31 (C = 0.0368 g/ml THF) at such a rate that the temperature does not go above 25C. After the addition, the temperature of the reaction mixture is slowly raised to 100C and held at that temperature for one hour. After cooling the mixture in an ice-acetone bath, 85 ml concentrated ammonia is added at such a rate that the temperature does not exceed 25C. The mixture is extracted five times with methylene chloride, the combined extracts dried and concentrated, giving 11.95 g of white solid, mp 79C-81C and [alpha] [25/D ] = +57.43 (C = 0.0213 g/ml THF). This solid is recrystallized from methylene chloride-hexane to give 11.2 g of (+)-2-amino-2,3-dimethylbutyramide, mp 81C-82C and [alpha] [25/D ] = +59.38 (C = 0.0162 g/ml THF).
With sulfuric acid; ammonia; In ice-acetone; EXAMPLE 78 Preparation of 2-amino-2,3-dimethylbutyramide STR251 Concentrated sulfuric acid (29.7 ml) is cooled with stirring in an ice-acetone cooling bath. To the acid is added 11.8 g (-)-2-amino-2,3-dimethylbutyronitrile with [alpha]D25 =-7.31 (C=0.0368 g/ml THF) at such a rate that the temperature does not go above 25 C. After the addition, the temperature of the reaction mixture is slowly raised to 100 C. and held at that temperature for one hour. After cooling the mixture in an ice-acetone bath, 85 ml concentrated ammonia is added at such a rate that the temperature does not exceed 75 C. The mixture is extracted five times with methylene chloride, the combined extracts dried and concentrated. This gives 11.95 g of white solid, mp 79-81 C. and [alpha]D25 =+57.43 (c=0.0213 g/ml THF). This solid is recrystallized from methylene chloride-hexane to give 11.2 g of (+)-2-amino-2,3-dimethylbutyramide, mp 81-82

  • 2
  • [ 1336-21-6 ]
  • [ 13893-53-3 ]
  • [ 40963-14-2 ]
YieldReaction ConditionsOperation in experiment
With sulfuric acid; In ice-acetone; EXAMPLE 3 Preparation of 2-amino-2,3-dimethylbutyramide STR14 To concentrated sulfuric acid (29.7 ml), cooled with stirring in an ice-acetone cooling bath, is added 11.8 g (-)-2-amino-2,3-dimethylbutyronitrile with [alpha]D25 =7.31 (c=0.0368 g/ml THF) at such a rate that the temperature does not go above 25 C. After the addition, the temperature of the reaction mixture is slowly raised to 100 C. and held at that temperature for one hour. After cooling the mixture in an ice-acetone bath, 85 ml concentrated ammonium hydroxide is added at such a rate that the temperature does not exceed 75 C. The mixture is extracted five times with methylene chloride, the combined extracts dried and concentrated. This gives 11.95 g of white solid, mp 79-81 C. and [alpha]D25 =+57.43 (c=0.0213 g/ml THF). This solid is recrystallized from methylene chloride-hexane to give 11.2 g of (+)-2-amino-2,3-dimethylbutyramide, mp 81-82 C. [ alpha]D25 =+59.38 (c=0.0162 g/ml THF).
With sulfuric acid; In ice-acetone; EXAMPLE 4 Preparation of 2-amino-2,3-dimethylbutyramide STR20 To concentrated sulfuric acid (29.7 ml), cooled with stirring in an ice-acetone cooling bath, is added 11.8 g (-)-2-amino-2,3-dimethylbutyronitrile with [alpha]D25 =7.31 (c=0.0368 g/ml THF) at such arate that the temperature does not go above 25 C. After the addition, the temperature of the reaction mixture is slowly raised to 100 C. and held at that temperature for one hour. After cooling the mixture in an ice-acetone bath, 85 ml concentrated ammonium hydroxide is added at such a rate that the temperature does not exceed 75 C. The mixture is extracted five times with methylene chloride, the combined extracts dried and concentrated. This gives 11.95 g of white solid, mp 79-81 C. and [alpha]D25 =+57.43 (c=0.0213 g/ml THF). This solid is recrystallized from methylene chloride-hexane to give 11.2 g of (+)-2-amino-2,3-dimethylbutyramide, mp 81-82 C. [alpha ]D25 =+59.38 (c=0.0162 g/ml THF).
 

Historical Records

Technical Information

Categories