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Chemical Structure| 139937-37-4 Chemical Structure| 139937-37-4

Structure of 139937-37-4

Chemical Structure| 139937-37-4

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Product Details of [ 139937-37-4 ]

CAS No. :139937-37-4
Formula : C7H6BrClO2S
M.W : 269.54
SMILES Code : CC1=C(C=CC(Br)=C1)S(Cl)(=O)=O
MDL No. :MFCD00219927
InChI Key :KNBSFUSBZNMAKU-UHFFFAOYSA-N
Pubchem ID :2781338

Safety of [ 139937-37-4 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P261-P280-P305+P351+P338-P310
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 139937-37-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 139937-37-4 ]

[ 139937-37-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 139937-37-4 ]
  • [ 79-08-3 ]
  • [ 99768-21-5 ]
YieldReaction ConditionsOperation in experiment
205 mg 4-Bromo-2-methyl-l-(methylsulfonyl)benzene for Example 35235 mg Sodium sulfite and 470 mg NaHC03 were dissolved in 1.75 mL of water and heated to 75C. 500 mg of 4-Bromo-2-methyl-benzenesulfonyl chloride were added in portions within 10 min (gas formation) and the mixture stirred for 1 h at 75C. 387 mg of Bromoacetic acid and 150 of water was added in small portions and the mixture stirred at 105C overnight. After cooling to 25C the mixture was acidified to pH 1 using 4N HCl. The resulting precipitate was collected and washed with water to yield 205 mg solid.Analysis: HPLC-MS: Rt = 0.73 (method X001 002) M+H = 249/251
205 mg 4.1.4.1. Synthesis of R2-Hal 4-Bromo-2-methyl-1-(methylsulfonyl)benzene for Example 35[0181] Sodium sulfite and 470 mg NaHCO3 were dissolved in 1.75 mL of water and heated to 75 C. 500 mg of 4-Bromo-2-methyl-benzenesulfonyl chloride were added in portions within 10 min (gas formation) and the mixture stirred for 1 h at 75 C. 387 mg of Bromoacetic acid and 150 μL of water was added in small portions and the mixture stirred at 105 C. overnight. After cooling to 25 C. the mixture was acidified to pH 1 using 4N HCl. The resulting precipitate was collected and washed with water to yield 205 mg solid.[0183]Analysis: HPLC-MS: Rt=0.73 (method X001-002) M+H=249/251
 

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