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Chemical Structure| 14100-97-1 Chemical Structure| 14100-97-1

Structure of 14100-97-1

Chemical Structure| 14100-97-1

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Product Details of [ 14100-97-1 ]

CAS No. :14100-97-1
Formula : C8H16O3S
M.W : 192.28
SMILES Code : CS(=O)(OCC1CCCCC1)=O
MDL No. :MFCD09869038

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Application In Synthesis of [ 14100-97-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 14100-97-1 ]

[ 14100-97-1 ] Synthesis Path-Downstream   1~1

  • 1
  • potassium cyanide [ No CAS ]
  • [ 14100-97-1 ]
  • [ 4435-14-7 ]
YieldReaction ConditionsOperation in experiment
In N,N-dimethyl-formamide; at 90℃; for 16h; A mixture of cyclohexylmethyl methanesulfonate (14, 30.16 mmol, 5.80 g, 1.00 eq.) and KCN (66.36 mmol, 4.32 g, 2.20 eq.) in DMF (30 mL) was stirred at 90C for 16 h. After cooling to room temperature, the reaction mixture was poured into LLO (100 mL). The aqueous layer was extracted with EtiO (3 x 100 mL). The combined organic layers were washed with brine (2 x 100 mL), dried over Na2S04 and concentrated under reduced pressure. The crude product 2-cyclohexylacetonitrile (8e, 4. l3g, 111%) used further without additional purification
 

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