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Chemical Structure| 1415501-19-7 Chemical Structure| 1415501-19-7

Structure of 1415501-19-7

Chemical Structure| 1415501-19-7

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Product Details of [ 1415501-19-7 ]

CAS No. :1415501-19-7
Formula : C16H12F2N2O3
M.W : 318.28
SMILES Code : O=C(C1=C(C)N=C2C(OCC3=C(F)C=CC=C3F)=CC=CN21)O
MDL No. :MFCD28098149

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Application In Synthesis of [ 1415501-19-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1415501-19-7 ]

[ 1415501-19-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1415501-19-7 ]
  • [ 2369-29-1 ]
  • N-(2-amino-3,5-difluorophenyl)-8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]pyridine-3-carboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
5% With 4-methyl-morpholine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; In N,N-dimethyl-formamide; at 20℃; 17 mg (0.12 mmol) of 3,5-difluorobenzene-1,2- diamine were initially charged, a solution of 32 mg (0.10 mmol) of 8-[(2,6-difluorobenzyl)oxy] -2-methylimidazo[1, 2-a]pyridine-3-carboxylic acid from Example 3A in 0.4 ml of DMF, a solution of 42mg (0.13 mmol) of TI3TU in 0.2 ml of DMF and then 20 mg (0.20 mmol) of 4-methylmor- pholine were added and the mixture was shaken at RT overnight. The target compound was isolated by preparative HPLC (Method 6). 3 mg (5% of theory) were obtained.10758] LC-MS (Method 5): R=0.99 mm10759] MS (ESpos): mlz=445 (M+H)
 

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