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Chemical Structure| 142179-84-8 Chemical Structure| 142179-84-8

Structure of 142179-84-8

Chemical Structure| 142179-84-8

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Product Details of [ 142179-84-8 ]

CAS No. :142179-84-8
Formula : C6H6IN
M.W : 219.02
SMILES Code : ICC1=CC=CN=C1
MDL No. :MFCD06410706

Safety of [ 142179-84-8 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H315-H318-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P310-P332+P313-P362-P403+P233-P405-P501
Class:8
UN#:3265
Packing Group:

Application In Synthesis of [ 142179-84-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 142179-84-8 ]

[ 142179-84-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 142179-84-8 ]
  • [ 4498-72-0 ]
  • [ 1415509-12-4 ]
YieldReaction ConditionsOperation in experiment
64% General procedure: A solution of <strong>[4498-72-0]1-(1H-indazol-3-yl)ethanone</strong> 11 [13] (5.0 g, 31.24 mmol) in dry dimethylformamide (150 mL) cooling on an icebath was treated with sodium hydride (1.39 g, 34.40 mmol). The reaction mixture was warmed to room temperature and stirred for 1 h before being cooled to 0 C, after which alkyl iodide (37.50 mmol) was added dropwise. The mixture was then stirred at r.t. for a further 3 h. Water (10 mL) was added and the mixture was extracted with ethyl acetate (3 × 100 mL), dried with MgSO4 and evaporated. The residue was purified by flash chromatography (Pet/EtOAc 5/1).
 

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