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Chemical Structure| 142230-98-6 Chemical Structure| 142230-98-6

Structure of 142230-98-6

Chemical Structure| 142230-98-6

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Product Details of [ 142230-98-6 ]

CAS No. :142230-98-6
Formula : C13H14N2O
M.W : 214.26
SMILES Code : O=CC1=C(C)N(C2=NC=CC=C2C)C(C)=C1
MDL No. :MFCD07643249

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Application In Synthesis of [ 142230-98-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 142230-98-6 ]

[ 142230-98-6 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 5676-56-2 ]
  • [ 142230-98-6 ]
  • (E)-5-bromo-2-(2-(2,5-dimethyl-1-(3-methylpyridin-2-yl)-1H-pyrrol-3-yl)vinyl)benzo[d]oxazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
58% With potassium tert-butylate; In tetrahydrofuran; at 20℃; for 3h; [0579] Compound 81c: To a solution of Comp-81b (0.4 g, 1.88 mmol) and Comp-8e (0.4 g, 1.88 mmol) in THF (10 mL) was added t-BuOK (0.2 g, 1.88 mmol) and the reaction mixture was stirred at RT for 3 h. Progress of the reaction was monitored by TLC and LCMS. After completion, the reaction mixture was concentrated under reduced pressure. The crude obtained was purified by column chromatography (silica, 230-400 mesh, 30% EtOAc in Hexane) to afford (E)-5-bromo-2-(2-(2,5-dimethyl-l-(3-methylpyridin-2-yl)-lH-pyrrol-3- yl)vinyl)benzo[d]oxazole (81c; 0.45 g, 58%) as a yellow solid. (1011) [0580] MS (ESI) m/e [M+H]+ Rt/%: 410.10/2.40/86.44%
  • 2
  • [ 5676-56-2 ]
  • [ 142230-98-6 ]
  • (E)-5-(4,4-difluoropiperidin-1-yl)-2-(2-(2,5-dimethyl-1-(3-methylpyridin-2-yl)-1H-pyrrol-3-yl)vinyl)benzo[d]oxazole [ No CAS ]
 

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