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Chemical Structure| 14503-45-8 Chemical Structure| 14503-45-8

Structure of 14503-45-8

Chemical Structure| 14503-45-8

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Product Details of [ 14503-45-8 ]

CAS No. :14503-45-8
Formula : C8H9ClO2
M.W : 172.61
SMILES Code : COC1=CC=C(C=C1Cl)CO
MDL No. :MFCD04124803
InChI Key :TZHJVLGDHRXGDX-UHFFFAOYSA-N
Pubchem ID :4312004

Safety of [ 14503-45-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H319
Precautionary Statements:P305+P351+P338

Application In Synthesis of [ 14503-45-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 14503-45-8 ]

[ 14503-45-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 4903-09-7 ]
  • [ 14503-45-8 ]
YieldReaction ConditionsOperation in experiment
With sodium borohydrid; In tetrahydrofuran; ethanol; PREPARATION 44 To a solution of <strong>[4903-09-7]3-chloro-4-methoxybenzaldehyde</strong> (156 g) in a mixture of ethanol (750 ml) and tetrahydrofuran (500 ml) was added sodium borohydride (25 g) under ice-cooling. After stirring at ambient temperature for 2 hours, the mixture was partitioned between ethyl acetate and water. The organic layer was washed with water, 1N-hydrochloric acid, water, aqueous sodium bicarbonate and brine, successively, and dried over magnesium sulfate. Evaporation of the solvent gave 3-chloro-4-methoxybenzyl alcohol (164 g) as a yellow oil. NMR(CDCl3, delta): 1.70 (1H, t, J=7 Hz), 3.90 (3H, s), 4.60 (2H, d, J=7 Hz), 6.90 (1H, d, J=8 Hz), 7.22 (1H, dd, J=4 Hz, 8 Hz), 7.39 (1H, d, J=4 Hz).
 

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