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Chemical Structure| 1459793-02-2 Chemical Structure| 1459793-02-2

Structure of 1459793-02-2

Chemical Structure| 1459793-02-2

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Product Details of [ 1459793-02-2 ]

CAS No. :1459793-02-2
Formula : C8H10ClNO
M.W : 171.62
SMILES Code : N[C@@H]1COC2=CC=CC=C12.[H]Cl
MDL No. :MFCD28383841
InChI Key :IVRJMBYBAPVRHB-OGFXRTJISA-N
Pubchem ID :119030525

Safety of [ 1459793-02-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 1459793-02-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1459793-02-2 ]

[ 1459793-02-2 ] Synthesis Path-Downstream   1~8

  • 1
  • [ 533-58-4 ]
  • [ 1459793-02-2 ]
  • 2
  • [ 24892-63-5 ]
  • [ 1459793-02-2 ]
  • 3
  • [ 1248949-73-6 ]
  • [ 1459793-02-2 ]
  • 4
  • [ 1459793-10-2 ]
  • [ 1459793-02-2 ]
  • 5
  • (R)-N-((S)-2,3-dihydrobenzofuran-3-yl)-2,4,6-trimethylbenzenesulfinamide [ No CAS ]
  • [ 1459793-02-2 ]
  • 6
  • [ 1459793-02-2 ]
  • [ 100-52-7 ]
  • C15H13NO [ No CAS ]
YieldReaction ConditionsOperation in experiment
With triethylamine; In methanol; at 50.0℃; for 2.0h; General procedure: Amine (1 equiv.) and aldehyde (1 equiv.) were dissolved in MeOH. When amine hydrochloride was used, an equivalent amount of Et3N was added. The mixture was stirred for 2h at 50C. After being cooled to room temperature, carboxylic acid (1 equiv.) and 4-phenylcyclohenen-1-yl isocyanide (1 equiv.) were added to the solution. The mixture was stirred 5-12h at 50-60C, and then concentrated in vacuo. The residue was suspended in a mixture of 1,4-dioxane and water, then added a solution of HCl in 1,4-dioxane (4mol/L). The mixture was stirred for 1h at room temperature. A saturated aqueous solution of NaHCO3 and EtOAc were added to the reaction mixture. The organic layer was washed with water and brine, and dried over anhydrous MgSO4. The solution was concentrated in vacuo, and the residue was purified using silica gel column chromatography.
  • 7
  • [ 1459793-02-2 ]
  • C35H32N2O3 [ No CAS ]
  • 8
  • [ 1459793-02-2 ]
  • N-[(R)-carbamoylphenylmethyl]-N-[(S)-2,3-dihydrobenzofuran-3-yl]benzamide [ No CAS ]
  • N-[(S)-carbamoylphenylmethyl]-N-[(S)-2,3-dihydrobenzofuran-3-yl]benzamide [ No CAS ]
 

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Technical Information

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Related Functional Groups of
[ 1459793-02-2 ]

Amines

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Related Parent Nucleus of
[ 1459793-02-2 ]

Benzofurans

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Chemical Structure| 1199782-77-8

A483270 [1199782-77-8]

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Chemical Structure| 2177263-68-0

A843755 [2177263-68-0]

(R)-6-Methyl-2,3-dihydrobenzofuran-3-amine hydrochloride

Similarity: 0.98