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Chemical Structure| 1463053-89-5 Chemical Structure| 1463053-89-5

Structure of 1463053-89-5

Chemical Structure| 1463053-89-5

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Product Details of [ 1463053-89-5 ]

CAS No. :1463053-89-5
Formula : C11H13BrClNO2
M.W : 306.58
SMILES Code : O=C(OC(C)(C)C)NC1=CC=CC(Cl)=C1Br

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* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1463053-89-5 ]

[ 1463053-89-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1463053-89-5 ]
  • [ 96558-73-5 ]
YieldReaction ConditionsOperation in experiment
77% With trifluoroacetic acid; In dichloromethane; at 20℃; for 3h; Step B: 2-bromo-3-chloroaniline [0186] To tert-butyl (2-bromo-3-chlorophenyl)carbamate (0.4 g) in DCM (20 mL) was added TFA (10 mL). The reaction mixture was stirred at RT for 3 hours and then concentrated. Water (10 mL) was added to the residue, and the mixture was extracted with DCM (2 x 20 mL). The organic phase was separated, washed with aqueous saturated NaHC03 and saturated NaCl, dried over anhydrous Na2S04, and concentrated to give the title compound as a solid (0.2 g, 77%). 1H NMR (400 MHz, CDC13) delta 7.03-6.99 (IH, m), 6.85- 6.83 (IH, d, J=8.0 Hz), 6.65-6.63 (IH, d, J=8.0 Hz), 4.25 (2H, s).
 

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