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Chemical Structure| 14950-55-1 Chemical Structure| 14950-55-1

Structure of 14950-55-1

Chemical Structure| 14950-55-1

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Product Details of [ 14950-55-1 ]

CAS No. :14950-55-1
Formula : C10H14O3
M.W : 182.22
SMILES Code : CC(O)C1=CC(OC)=CC(OC)=C1
MDL No. :MFCD19601840

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Application In Synthesis of [ 14950-55-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 14950-55-1 ]

[ 14950-55-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 14950-55-1 ]
  • [ 4983-28-2 ]
  • [ 1453211-59-0 ]
YieldReaction ConditionsOperation in experiment
415 mg With tributylphosphine; 1,1'-azodicarbonyl-dipiperidine; In tetrahydrofuran; at 20 - 50℃; for 15h;Cooling with ice; Preparation Example 15 A mixture of <strong>[4983-28-2]2-chloro-5-hydroxypyrimidine</strong> (487 mg) and 1-(3,5-dimethoxyphenyl)ethanol (680 mg), tributylphosphine (1.37 mL), and tetrahydrofuran (14 mL) was ice cooled, and 1,1'-(azodicarbonyl)dipiperidine (1.4 g) was added thereto followed by stirring at room temperature for 12 hours and stirring at 50° C. for 3 hours. Insoluble materials were removed by filtration and the filtrate was concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography (ethyl acetate/hexane) to give 2-chloro-5-[1-(3,5-dimethoxyphenyl)ethoxy]pyrimidine (415 mg).
 

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