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Chemical Structure| 151239-47-3 Chemical Structure| 151239-47-3

Structure of 151239-47-3

Chemical Structure| 151239-47-3

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Product Details of [ 151239-47-3 ]

CAS No. :151239-47-3
Formula : C14H11BrO2
M.W : 291.14
SMILES Code : O=C(C1=CC=C(Br)C=C1)C2=CC=CC(OC)=C2
MDL No. :MFCD01311563

Safety of [ 151239-47-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H317-H319
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 151239-47-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 151239-47-3 ]

[ 151239-47-3 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 151239-47-3 ]
  • [ 182344-13-4 ]
  • [ 1357563-67-7 ]
YieldReaction ConditionsOperation in experiment
51% With tetrakis(triphenylphosphine) palladium(0); caesium carbonate; In 1,2-dimethoxyethane; water; at 80℃;Inert atmosphere; General procedure: A mixture of arylbromide (1 equiv), boronic acid (1.2 equiv), cesium carbonate (4 equiv), and tetrakis(triphenylphosphine) palladium (0.02 equiv) was suspended in a DME/water (2:1) solution and the mixture was degazed. The mixture was heated to 80 °C and stirred overnight at 80 °C under nitrogen. The reaction mixture was cooled to room temperature, quenched by water and extracted with ethyl acetate. The organic layer was washed with brine, dried over sodium sulfate, filtered and concentrated to dryness. The product was purified by column chromatography or by recrystallisation.
  • 2
  • [ 151239-47-3 ]
  • [ 175883-62-2 ]
  • [ 1357563-62-2 ]
YieldReaction ConditionsOperation in experiment
With tetrakis(triphenylphosphine) palladium(0); caesium carbonate; In 1,2-dimethoxyethane; water; at 80℃;Inert atmosphere; General procedure: A mixture of arylbromide (1 equiv), boronic acid (1.2 equiv), cesium carbonate (4 equiv), and tetrakis(triphenylphosphine) palladium (0.02 equiv) was suspended in a DME/water (2:1) solution and the mixture was degazed. The mixture was heated to 80 C and stirred overnight at 80 C under nitrogen. The reaction mixture was cooled to room temperature, quenched by water and extracted with ethyl acetate. The organic layer was washed with brine, dried over sodium sulfate, filtered and concentrated to dryness. The product was purified by column chromatography or by recrystallisation.
  • 3
  • [ 151239-47-3 ]
  • [ 219735-99-6 ]
  • [ 1357563-65-5 ]
YieldReaction ConditionsOperation in experiment
61% With tetrakis(triphenylphosphine) palladium(0); caesium carbonate; In 1,2-dimethoxyethane; water; at 80℃;Inert atmosphere; General procedure: A mixture of arylbromide (1 equiv), boronic acid (1.2 equiv), cesium carbonate (4 equiv), and tetrakis(triphenylphosphine) palladium (0.02 equiv) was suspended in a DME/water (2:1) solution and the mixture was degazed. The mixture was heated to 80 C and stirred overnight at 80 C under nitrogen. The reaction mixture was cooled to room temperature, quenched by water and extracted with ethyl acetate. The organic layer was washed with brine, dried over sodium sulfate, filtered and concentrated to dryness. The product was purified by column chromatography or by recrystallisation.
 

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