Home Cart 0 Sign in  

[ CAS No. 153645-26-2 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 153645-26-2
Chemical Structure| 153645-26-2
Structure of 153645-26-2 * Storage: {[proInfo.prStorage]}

Quality Control of [ 153645-26-2 ]

Related Doc. of [ 153645-26-2 ]

SDS
Alternatived Products of [ 153645-26-2 ]
Alternatived Products of [ 153645-26-2 ]

Product Details of [ 153645-26-2 ]

CAS No. :153645-26-2 MDL No. :MFCD01861301
Formula : C11H23NO3 Boiling Point : -
Linear Structure Formula :- InChI Key :N/A
M.W :217.31 g/mol Pubchem ID :10376058
Synonyms :

Safety of [ 153645-26-2 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P264-P270-P301+P312-P330 UN#:N/A
Hazard Statements:H302 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 153645-26-2 ]

  • Upstream synthesis route of [ 153645-26-2 ]
  • Downstream synthetic route of [ 153645-26-2 ]

[ 153645-26-2 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 153645-26-2 ]
  • [ 62965-35-9 ]
YieldReaction ConditionsOperation in experiment
73% at 0 - 25℃; In a four-neck flask, 10.0 g (1.0 eq) of N-Boc-t-butyl ethylamine alcohol compound was added. Isopropyl acetate 100ml, sodium bromide 2.0eq, sodium bicarbonate 2.0eq, TMEPO 0.05eq, Cool to 0-5 °C. Temperature control 0 ~ 5 °C, sodium hypochlorite drops 1.2eq, about 1.0 ~ 1.5h drops, heat 2h, Warm up to 20 ~ 25 °C, heat 1.0 ~ 2.0h. Sodium thiosulfate solid 0.6 eq was added and incubated for 0.5 h. The aqueous layer was further extracted with 20 ml isopropyl acetate and the phases separated. Add 20 ml of isopropyl acetate to the aqueous layer, add citric acid, adjust the pH to 2 to 3, separate the phases, extract the aqueous layer with 20 ml of x 2 isopropyl acetate, combine the organic layers, add 50 ml of water to wash, separate the phases, and then apply the organic layer. Dry with 0.5g anhydrous magnesium sulfate 0.5h, suction filtration, the filtrate was evaporated to dryness at 40 ~ 50 °C, 40 ~ 50 °C insulation, 5ml of isopropyl acetate was added, 25ml of heptane was added dropwise, slowly cooling and crystallization, 20 ~ 30 °C heat 0.5h, suction filtration, washing, 7.8g boutique, yield 73percent. Optical purity 100percent.
Reference: [1] Patent: CN107778192, 2018, A, . Location in patent: Paragraph 0060-0062
Historical Records

Related Functional Groups of
[ 153645-26-2 ]

Amines

Chemical Structure| 169556-48-3

[ 169556-48-3 ]

N-Boc-DL-valinol

Similarity: 0.98

Chemical Structure| 107202-39-1

[ 107202-39-1 ]

(S)-tert-Butyl (1-cyclohexyl-2-hydroxyethyl)carbamate

Similarity: 0.94

Chemical Structure| 188348-00-7

[ 188348-00-7 ]

(R)-tert-Butyl (1-cyclohexyl-2-hydroxyethyl)carbamate

Similarity: 0.94

Chemical Structure| 150736-71-3

[ 150736-71-3 ]

(R)-tert-Butyl (1-hydroxybutan-2-yl)carbamate

Similarity: 0.93

Chemical Structure| 150736-72-4

[ 150736-72-4 ]

(S)-tert-Butyl (1-hydroxybutan-2-yl)carbamate

Similarity: 0.93

Aliphatic Chain Hydrocarbons

Chemical Structure| 169556-48-3

[ 169556-48-3 ]

N-Boc-DL-valinol

Similarity: 0.98

Chemical Structure| 150736-71-3

[ 150736-71-3 ]

(R)-tert-Butyl (1-hydroxybutan-2-yl)carbamate

Similarity: 0.93

Chemical Structure| 150736-72-4

[ 150736-72-4 ]

(S)-tert-Butyl (1-hydroxybutan-2-yl)carbamate

Similarity: 0.93

Chemical Structure| 157035-77-3

[ 157035-77-3 ]

(S)-tert-Butyl (2-hydroxy-2,4-dimethylpentan-3-yl)carbamate

Similarity: 0.92

Chemical Structure| 1353743-61-9

[ 1353743-61-9 ]

tert-Butyl (1,3-dihydroxy-3-methylbutan-2-yl)carbamate

Similarity: 0.92

Amides

Chemical Structure| 169556-48-3

[ 169556-48-3 ]

N-Boc-DL-valinol

Similarity: 0.98

Chemical Structure| 107202-39-1

[ 107202-39-1 ]

(S)-tert-Butyl (1-cyclohexyl-2-hydroxyethyl)carbamate

Similarity: 0.94

Chemical Structure| 188348-00-7

[ 188348-00-7 ]

(R)-tert-Butyl (1-cyclohexyl-2-hydroxyethyl)carbamate

Similarity: 0.94

Chemical Structure| 150736-71-3

[ 150736-71-3 ]

(R)-tert-Butyl (1-hydroxybutan-2-yl)carbamate

Similarity: 0.93

Chemical Structure| 150736-72-4

[ 150736-72-4 ]

(S)-tert-Butyl (1-hydroxybutan-2-yl)carbamate

Similarity: 0.93

Alcohols

Chemical Structure| 169556-48-3

[ 169556-48-3 ]

N-Boc-DL-valinol

Similarity: 0.98

Chemical Structure| 107202-39-1

[ 107202-39-1 ]

(S)-tert-Butyl (1-cyclohexyl-2-hydroxyethyl)carbamate

Similarity: 0.94

Chemical Structure| 188348-00-7

[ 188348-00-7 ]

(R)-tert-Butyl (1-cyclohexyl-2-hydroxyethyl)carbamate

Similarity: 0.94

Chemical Structure| 150736-71-3

[ 150736-71-3 ]

(R)-tert-Butyl (1-hydroxybutan-2-yl)carbamate

Similarity: 0.93

Chemical Structure| 150736-72-4

[ 150736-72-4 ]

(S)-tert-Butyl (1-hydroxybutan-2-yl)carbamate

Similarity: 0.93