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Chemical Structure| 15563-40-3 Chemical Structure| 15563-40-3

Structure of 15563-40-3

Chemical Structure| 15563-40-3

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Product Details of [ 15563-40-3 ]

CAS No. :15563-40-3
Formula : C12H15NS
M.W : 205.32
SMILES Code : S=C(C1=CC=CC=C1)N2CCCCC2

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Application In Synthesis of [ 15563-40-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 15563-40-3 ]

[ 15563-40-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 15563-40-3 ]
  • [ 2905-56-8 ]
YieldReaction ConditionsOperation in experiment
90% With bromopentacarbonylmanganese(I); hydrogen; triethylamine; copper(I) bromide; at 100℃; under 22502.3 Torr; for 1h;Autoclave; Into a 14mL polytetrafluoroethylene lined reaction tube, add the catalyst pentacarbonyl manganese bromide (0.0375mmol, 10.3mg),Reaction substrate N-thiobenzoyl piperidine (0.5mmol, 102.5mg), cuprous bromide (1.25mmol, 180mg), solvent hexafluoroisopropanol (2.5mL) and triethylamine (1.5mmol, 151.5 mg), place the reaction tube in the autoclave and fill it with 3MPa hydrogen.React at 100 C., after 1 hour, cool to room temperature, release gas, rinse the reaction tube with ethyl acetate, pass through a short silica gel column, and spin dry.After purification by column chromatography (eluent: petroleum ether: triethylamine = 40/1, v/v), 78 mg of the target product (formula I-a) was obtained, and the yield was 90%.
 

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