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Chemical Structure| 1566-42-3 Chemical Structure| 1566-42-3

Structure of 1566-42-3

Chemical Structure| 1566-42-3

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Product Details of [ 1566-42-3 ]

CAS No. :1566-42-3
Formula : C8H10N2O2
M.W : 166.18
SMILES Code : O=C(N)NC1=CC=C(OC)C=C1
MDL No. :MFCD00014789

Safety of [ 1566-42-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Application In Synthesis of [ 1566-42-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1566-42-3 ]

[ 1566-42-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2293-07-4 ]
  • [ 1566-42-3 ]
YieldReaction ConditionsOperation in experiment
84% With trans-3,5-dihydroperoxy-3,5-dimethyl-1,2-dioxolane; water; potassium hydroxide; In acetonitrile; at 20℃; for 0.166667h; To a stirred solution of phenylthiourea 1 (1mmol) and 5% aq. KOH (5 mL) in acetonitrile (5 mL) was added DHPDMDO (0.332 g, 2mmol). The resulting mixture was allowed to stir at room temperature for an appropriate time (Table 2). After completion of the reaction as monitored by TLC, the reaction mixture was diluted with water (10mL) and the product was extracted in dichloromethan (3×5mL). The combined organic layer was washed with water (2×5mL) and dried over anhydrous Na2SO4. Evaporation of the solvent under reduced pressure gave almost pure products. Structures of the known products were established on the basis of their physical and spectroscopic (IR, 1H-NMR and 13C-NMR) data, which were consistent with those reported.[34,61]
 

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