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Chemical Structure| 1567-14-2 Chemical Structure| 1567-14-2

Structure of 1567-14-2

Chemical Structure| 1567-14-2

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Product Details of [ 1567-14-2 ]

CAS No. :1567-14-2
Formula : C7H12O2
M.W : 128.17
SMILES Code : CC/C=C(C)/C(OC)=O
MDL No. :MFCD00075270

Safety of [ 1567-14-2 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H225
Precautionary Statements:P501-P240-P210-P233-P243-P241-P242-P280-P370+P378-P303+P361+P353-P403+P235
Class:3
UN#:3272
Packing Group:

Application In Synthesis of [ 1567-14-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1567-14-2 ]

[ 1567-14-2 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 67-56-1 ]
  • [ 16957-70-3 ]
  • [ 1567-14-2 ]
YieldReaction ConditionsOperation in experiment
91% sulfuric acid; for 16h;Heating / reflux; 2-Methylpent-2-enoic acid methyl ester (16B). A mixture of <strong>[16957-70-3]2-methylpent-2-enoic acid</strong> (5.0 g, 44 mmol) and sulfuric acid (0.5 mL) in methanol (250 mL) was heated at reflux for 16 hours. The solution was allowed to cool down to 20 C and concentrated under reduced pressure. The residue was dissolved in ethyl acetate (100 mL) and washed with saturated aqueous sodium hydrogen carbonate (2 x 50 mL), distilled water (50 mL), then with brine (50 mL). The organic layer was dried over anhydrous MGS04, filtered and concentrated under reduced pressure to give the title compound (5.1 g, 91percent) as a colourless oil.
  • 2
  • [ 1567-14-2 ]
  • [ 1617-37-4 ]
  • [ 16957-70-3 ]
  • 4
  • [ 16957-70-3 ]
  • [ 122-51-0 ]
  • [ 1567-14-2 ]
YieldReaction ConditionsOperation in experiment
With sulfuric acid; sodium hydrogencarbonate; In methanol; EXAMPLE 1 methyl (2E)-2-methyl-2-pentenoate A solution of <strong>[16957-70-3](2E)-2-methyl-2-pentenoic acid</strong> (1027 g), triethylformate (1031 g), and concentrated H2SO4 (24 mL) in methanol (3.23L) was stirred at reflux for 10 hours, cooled to ambient temperature, and treated with NaHCO3 (76 g). The methanol layer was isolated and distilled at 45 mm Hg to provide fractions which distilled at 38-42° C. and 68-72° C., the latter of which provided 820 g of desired product. The 38-42° C. fraction was concentrated to one-quarter of its original volume and redistilled to provide an additional 200 g of the desired product (88.5percent total) which azeotropes with methanol. 1H NMR (CDCl3) delta 6.8-6.72 (m, 1H), 3.73 (s, 3H), 2.5-2.2 (m, 2H), 1.83 (m, 3H) 1.04 (t, J=5.1 Hz, 3H).
  • 5
  • [ 16957-70-3 ]
  • [ 18107-18-1 ]
  • [ 1567-14-2 ]
 

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