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Chemical Structure| 15764-47-3 Chemical Structure| 15764-47-3

Structure of 15764-47-3

Chemical Structure| 15764-47-3

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Product Details of [ 15764-47-3 ]

CAS No. :15764-47-3
Formula : C12H9N3
M.W : 195.22
SMILES Code : C12=NC(C3=CC=CC=C3)=CN1C=CC=N2
MDL No. :MFCD00453235

Safety of [ 15764-47-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of [ 15764-47-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 15764-47-3 ]

[ 15764-47-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 15764-47-3 ]
  • [ 54439-75-7 ]
  • C20H13N3O2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
46% With tetrabutylammomium bromide; palladium diacetate; potassium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; Trimethylacetic acid; In water; nitrobenzene; at 110℃; for 48h; General procedure: Imidazo[1,2-a]pyrimidine (0.3 mmol), 2-chlorobenzaldehyde (0.9 mmol, 3 equiv.), K2CO3 (0.9 mmol, 3 equiv.), NBu4Br (0.3 mmol, 1 equiv.), PivOH (30 molpercent), Pd(OAc)2 (5 mol percent), and Xantphos (10 mol percent) were added to a 10 mL round-bottomed flask, and then a mixed solvent of 3 mL of PhNO2 and 30 uL of H2O was added. The mixture was stirred under air at 110 °C for 24 h. After the reaction was complete, the mixture was washed with water and extracted with ethyl acetate three times. The combined organic layer was dried with anhydrous MgSO4 and filtered. The filtrate was concentrated in vacuo. The crude product was purified by flash chromatography on silica gel using dichloromethane/methanol as the eluent to give the pure product.
 

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