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Chemical Structure| 160002-61-9 Chemical Structure| 160002-61-9

Structure of Fmoc-Glu(OtBu)-OMe
CAS No.: 160002-61-9

Chemical Structure| 160002-61-9

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Product Details of [ 160002-61-9 ]

CAS No. :160002-61-9
Formula : C25H29NO6
M.W : 439.50
SMILES Code : O=C(OC)[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CCC(OC(C)(C)C)=O
MDL No. :MFCD27578188

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Application In Synthesis of [ 160002-61-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 160002-61-9 ]

[ 160002-61-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 160002-61-9 ]
  • [ 145038-49-9 ]
YieldReaction ConditionsOperation in experiment
With triethylsilane; trifluoroacetic acid; In dichloromethane; at 20℃; General procedure: A dichloromethane solution (10 mL) of Fmoc-AA(OtBu)-OMe (0.3 mmol) was treated with trifluoroacetic acid (1.5 mL) and triethylsilane (0.25 mL) at room temperature. After a check of TLC showed that the starting tert-butyl ether had disappeared (stirring for 2?3 h), the reaction was quenched by addition of distilled water. The separated organic phase was washed with water, dried over sodium sulfate, and filtered. All the solvent was evaporated and the residue was purified with FCC (10 percent Et2O?CH2Cl2) and recrystallization (CH2Cl2?hexane) to give 5d/e (ca. 50?70 percent).
  • 2
  • [ 160002-61-9 ]
  • [ 53838-27-0 ]
 

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