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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
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Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 16088-19-0 Chemical Structure| 16088-19-0

Structure of 16088-19-0

Chemical Structure| 16088-19-0

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Product Details of [ 16088-19-0 ]

CAS No. :16088-19-0
Formula : C11H16N2O2
M.W : 208.26
SMILES Code : O=C(OC1=CC=CC(N(C)C)=C1)N(C)C
MDL No. :MFCD09753086

Safety of [ 16088-19-0 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H300-H310-H330
Precautionary Statements:P260-P264-P280-P284-P301+P310-P302+P350
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 16088-19-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 16088-19-0 ]

[ 16088-19-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 16088-19-0 ]
  • [ 77-78-1 ]
  • [ 51-60-5 ]
YieldReaction ConditionsOperation in experiment
85% In acetone; at 20℃;four neck round bottom flask; Example 9Preparation of neostigmine methylsulphate (General procedure)A 250 ml four neck round bottom flask was charged with 3-dimethylaminophenyl dimethylcarbamate obtained in the example 1, and acetone. Dimethyl sulphate (1.66 eq) was added drop wise to the flask at room temperature. The reaction mixture was stirred overnight, cooled to 5C to 10C for 2 hours, filtered and the filtrate was washed with isopropanol. The residue was dried under vacuum at room temperature to get crude neostigmine methylsulphate, which was purified by recrystallisation from isopropanol.Yield - 85%Nature - pale yellow oilHPLC Purity - 99.21%
 

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