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Chemical Structure| 164071-56-1 Chemical Structure| 164071-56-1

Structure of 164071-56-1

Chemical Structure| 164071-56-1

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Product Details of [ 164071-56-1 ]

CAS No. :164071-56-1
Formula : C7H9ClOS
M.W : 176.66
SMILES Code : O[C@@H](CCCl)C1=CC=CS1
MDL No. :MFCD07357309

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Application In Synthesis of [ 164071-56-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 164071-56-1 ]

[ 164071-56-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 30818-28-1 ]
  • [ 164071-56-1 ]
  • [ 357405-45-9 ]
YieldReaction ConditionsOperation in experiment
61% a 4-Chloro-2-[[(1R)-3-chloro-1-(2-thienyl)propyl]oxy]benzonitrile Using <strong>[30818-28-1]4-chloro-2-hydroxybenzonitrile</strong> (303 mg, 1.97 mmol) and (S)-alpha-(2-chloroethyl) thiophenemethanol (349 mg, 1.97 mmol), and the procedure described in Example 5(a), the title compound was prepared as a white crystalline solid (373 mg, 61percent). 1H NMR300 MHz (CDCl3) 7.48-7.45 (1H,d), 7.33-7.31 (1H,dd), 7.14-7.13 (1H,m), 7.03-6.97 (3H,m), 5.82-5.77 (1H,q), 3.91-3.83 (1H,m), 3.67-3.59 (1H,m), 2.70-2.63 (1H,m), 2.42-2.33 (1H,m).
 

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