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Chemical Structure| 169457-73-2 Chemical Structure| 169457-73-2

Structure of 169457-73-2

Chemical Structure| 169457-73-2

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Product Details of [ 169457-73-2 ]

CAS No. :169457-73-2
Formula : C12H22BrNO2
M.W : 292.21
SMILES Code : O=C(N1CCC(CCBr)CC1)OC(C)(C)C
MDL No. :MFCD06410598
InChI Key :CLBWAEYOPRGKBT-UHFFFAOYSA-N
Pubchem ID :10541625

Safety of [ 169457-73-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 169457-73-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 169457-73-2 ]

[ 169457-73-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 169457-73-2 ]
  • [ 180307-56-6 ]
YieldReaction ConditionsOperation in experiment
With potassium tert-butylate; In tetrahydrofuran; diethyl ether; (ix) 4-Vinyl-piperidine-1-carboxylic acid tert-butyl ester A solution of 4(2-bromo-ethyl)-piperidine-1-carboxylic acid tert-butyl ester (81.5 g 0.279 mol) in dry tetrahydrofuran (1000 ml) under nitrogen at 20 was treated portionwise, over 30 min, with potassium tert-butoxide (63.2 g 0.563 mol). The mixture was stirred at 25 for 3 h and partitioned between saturated aqueous ammonium chloride (1000 ml) and diethyl ether (500 ml). The aqueous phase was extracted with diethyl ether (4*500 ml) and the combined, dried (MgSO4) extracts were evaporated in vacuo. The residue was purified by flash column chromatography on silica gel (Merck 9385) eluant cyclohexane: diethyl ether (19:1) to give the title compound as an orange oil (37.1 g, 0.176 mol, 63%). Mass spectrum m/z=212 ?MH+!
 

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[ 169457-73-2 ]

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Related Parent Nucleus of
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