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Chemical Structure| 169883-36-7 Chemical Structure| 169883-36-7

Structure of 169883-36-7

Chemical Structure| 169883-36-7

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Product Details of [ 169883-36-7 ]

CAS No. :169883-36-7
Formula : C8H10BrNO2
M.W : 232.07
SMILES Code : COC1=CC(OC)=C(N)C=C1Br
MDL No. :MFCD14534267

Safety of [ 169883-36-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 169883-36-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 169883-36-7 ]

[ 169883-36-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 169883-36-7 ]
  • [ 145214-05-7 ]
  • 2,4-dimethoxy-5-(1,3-oxazol-2-yl)aniline [ No CAS ]
YieldReaction ConditionsOperation in experiment
58% tetrakis(triphenylphosphine) palladium(0); In 1,3-dioxane; at 95℃; for 3h; 5-Bromo-2,4-dimethoxyaniline (0.51 g), 2- (TRIBUTYLSTANNYL)-1, 3-oxazole (2.7 g), and Pd (Ph3P) 4 (0) (0. 11 g) are dissolved in dioxane (10 ML) and heated to 95oC for 3 hours The solvent removed in vacuo to give a reside that is taken up in EtOAc, washed with saturated KF, brine, dried (NA2S04), purified by silica gel chromatography to give 2, 4-DIMETHOXY-5- (1, 3-oxazol-2-yl) aniline. Yield 58%. MS (ESI+) for CLLHL2N203 MLZ 221. 1 (M+H) +.
 

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