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Chemical Structure| 171722-92-2 Chemical Structure| 171722-92-2

Structure of 171722-92-2

Chemical Structure| 171722-92-2

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Product Details of [ 171722-92-2 ]

CAS No. :171722-92-2
Formula : C18H20N2O2
M.W : 296.36
SMILES Code : O=C(NC1=CC=CC=C1C2=CC=CC=C2)OC3CCNCC3
MDL No. :MFCD27964656
InChI Key :AGZCCVMWUZINGV-UHFFFAOYSA-N
Pubchem ID :10851461

Safety of [ 171722-92-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 171722-92-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 171722-92-2 ]

[ 171722-92-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 124-63-0 ]
  • [ 171723-95-8 ]
  • [ 171722-92-2 ]
  • 1-(4-trifluoroacetamidobenzyl)-4-piperidyl N-(2-biphenylyl)carbamate [ No CAS ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; triethylamine; In N-methyl-acetamide; dichloromethane; Example 35 A 0.23 ml portion of methanesulfonyl chloride was added dropwise to 12 ml of an ice-cooled dichloromethane solution containing 0.64 g of N-[4-(hydroxymethyl)benzyl]trifluoroacetamide and 0.33 g of triethylamine, and the reaction mixture was stirred at room temperature for 3 hours. The reaction mixture was poured into water and extracted with dichloromethane and the resulting organic layer was washed with water and brine, and then dried over anhydrous sodium sulfate, and then the solvent was removed under reduced pressure. The resulting residue was dissolved in 5 ml of dimethylformamide and added dropwise to a mixture of 0.74 g of 4-piperidyl N-(2-biphenylyl)carbamate and 0.37 g of potassium carbonate suspended in 20 ml of ice-cooled dimethylformamide, and the reaction mixture was stirred at room temperature overnight. The reaction solution was poured into water and extracted with ethyl acetate, the resulting organic layer was washed with water and brine in that order and dried over anhydrous sodium sulfate and then the solvent was removed under reduced pressure. The resulting residue was purified by silica gel column chromatography (chloroform/methanol = 100/1) to give 1.19 g of 1-(4-trifluoroacetamidobenzyl)-4-piperidyl N-(2-biphenylyl)carbamate as pale yellow oil.
 

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