Home Cart Sign in  
Chemical Structure| 172529-94-1 Chemical Structure| 172529-94-1

Structure of 172529-94-1

Chemical Structure| 172529-94-1

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 172529-94-1 ]

CAS No. :172529-94-1
Formula : C10H14ClN5O2
M.W : 271.70
SMILES Code : OCC(CCN1C=NC2=C(Cl)N=C(N)N=C12)CO

Safety of [ 172529-94-1 ]

Application In Synthesis of [ 172529-94-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 172529-94-1 ]

[ 172529-94-1 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 108-24-7 ]
  • [ 172529-94-1 ]
  • [ 97845-60-8 ]
YieldReaction ConditionsOperation in experiment
80.8% With dmap; triethylamine; In dichloromethane; at 20℃; Dichloromethane 125ml (1.94mol), 2-amino-6-chloro-9-(3-hydroxymethyl-4-hydroxy-1-butyl)purine 15g (0.055mol), 4-dimethylaminopyridine 0.16g (0.001mol), 7.65g (0.076mol) of triethylamine was put into the reaction bottle and stirred, 23.4 g (0.23 mol) of acetic anhydride was added dropwise at RT. After the addition was complete, the reaction was incubated until TLC (dichloromethane: methanol = 10: 1 (V / V)) showed that the reaction was complete. Cool to 20 C and adjust the pH to 6.0-7.0 with 25% aqueous sodium hydroxide solution. After standing for separation, the organic layer was distilled under reduced pressure to near dryness, 40 ml of methanol / water (V / V = 3/1) was added, heated to full solution, slowly cooled to 4 C, and stirred for 1 h. Filtration and vacuum drying at 45-60 C gave 15.83 g of 2-amino-6-chloro-9-(3-acetoxymethyl-4-acetoxy-1-butyl)purine in 80.8% yield.
 

Historical Records

Technical Information

Categories