[ CAS No. 1737-36-6 ]

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Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 1737-36-6
Chemical Structure| 1737-36-6
Structure of 1737-36-6

Quality Control of [ 1737-36-6 ]

Purity: {[proInfo.showProBatch.pb_purity]}

Related Doc. of [ 1737-36-6 ]

SDS

Product Details of [ 1737-36-6 ]

CAS No. :1737-36-6MDL No. :MFCD01631468
Formula :C8H4ClF3O2Boiling Point :289.9°C at 760 mmHg
Linear Structure Formula :-InChI Key :-
M.W :224.56Pubchem ID :-
Synonyms :

Computed Properties of [ 1737-36-6 ]

TPSA : 37.3 H-Bond Acceptor Count : 5
XLogP3 : - H-Bond Donor Count : 1
SP3 : 0.13 Rotatable Bond Count : 1

Safety of [ 1737-36-6 ]

Signal Word:WarningClassN/A
Precautionary Statements:P261-P305+P351+P338UN#:N/A
Hazard Statements:H315-H319-H335Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 1737-36-6 ]

  • Upstream synthesis route of [ 1737-36-6 ]
  • Downstream synthetic route of [ 1737-36-6 ]

[ 1737-36-6 ] Synthesis Path-Upstream   1~3

  • 1
  • [ 445303-09-3 ]
  • [ 14660-45-8 ]
  • [ 1737-36-6 ]
YieldReaction ConditionsOperation in experiment
62% With chloro[1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene]copper(I) In tetrahydrofuran at 70℃; for 16.00 h; Inert atmosphere; Sealed tube General procedure: In a glovebox, Cu(IPr)Cl catalyst and PMC (62.8 mg, 0.55 mmol,1.1 equiv) were charged to a glass reaction tube. A solution of 3(0.50 mmol) in THF (1.5 mL) was added, the tube was sealed, taken out of the glovebox, and heated at 70 °C for 16 h. After cooling tor.t., H2O (2 mL) was added and the reaction mixture was acidified with aqueous HCl (1 M), and saturated with sodium chloride. After extraction with EtOAc (3 × 5 mL), the organic phase was dried overanhydrous sodium sulfate and concentrated under vacuo. The product was purified by silica gel column chromatography.
Reference: [1] Synthesis (Germany), 2014, vol. 46, # 14, p. 1881 - 1885
  • 2
  • [ 1735-54-2 ]
  • [ 1737-36-6 ]
Reference: [1] Patent: US2008/200535, 2008, A1. Location in patent: Page/Page column 164
[2] Organic Letters, 2015, vol. 17, # 1, p. 38 - 41
  • 3
  • [ 1735-54-2 ]
  • [ 1737-36-6 ]
Reference: [1] Patent: EP279698, 1990, A3
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