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Chemical Structure| 17413-73-9 Chemical Structure| 17413-73-9

Structure of 17413-73-9

Chemical Structure| 17413-73-9

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Product Details of [ 17413-73-9 ]

CAS No. :17413-73-9
Formula : C10H11ClO3
M.W : 214.65
SMILES Code : CC(C)(OC1=CC=CC(Cl)=C1)C(O)=O
MDL No. :MFCD01695660

Safety of [ 17413-73-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 17413-73-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 17413-73-9 ]

[ 17413-73-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 17413-73-9 ]
  • [ 62058-03-1 ]
  • 2-(3-chloro-phenoxy)-<i>N</i>-(5-hydroxy-adamantan-2-yl)-2-methyl-propionamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
Example B.18 a) Preparation of compound 43; To a mixture of 2-(3-chlorophenoxy)-2-methyl-propanoic acid [17413-73-9] (0.010 mol) and CH2Cl2 (70 ml), HOBt (0.012 mol) was added at room temperature. The mixture was stirred until complete dissolution of HOBt. EDCI (0.012 mol) was added and the mixture was stirred at room temperature for 30 minutes. (lalpha,3alpha,4alpha,5beta,7alpha)- 4-aminotricyclo[3.3.1.13'7]decan-l-ol [62058-03-1] (0.012 mol) was added and the mixture was stirred at room temperature overnight. The solvent was evaporated. The residue was dissolved in CH2CI2 and washed with 15percent citric acid solution, IM Na2CO3 and water. The organic layer was separated, dried (MgSO4), filtered and the solvent was evaporated. The residue was purified by column chromatography (eluent: CH2C12/CH3OH 100/0 to 98/2). Two product fraction groups were collected and the solvents were evaporated. The residue was crystallized from DIPE. The precipitate was filtered off and dried, yielding 1.97g of compound 43.
 

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