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Chemical Structure| 17422-74-1

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Product Details of 3-Formylchromone

CAS No. :17422-74-1
Formula : C10H6O3
M.W : 174.15
SMILES Code : O=CC1=COC2=CC=CC=C2C1=O
MDL No. :MFCD00014667
InChI Key :FSMYWBQIMDSGQP-UHFFFAOYSA-N
Pubchem ID :87112

Safety of 3-Formylchromone

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of 3-Formylchromone

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 17422-74-1 ]

[ 17422-74-1 ] Synthesis Path-Downstream   1~10

  • 1
  • [ 17422-74-1 ]
  • [ 1124-16-9 ]
  • [ 78831-28-4 ]
  • 2
  • [ 6971-44-4 ]
  • [ 17422-74-1 ]
  • [ 1017219-11-2 ]
  • 3
  • [ 17422-74-1 ]
  • [ 20028-40-4 ]
  • [ 949304-63-6 ]
  • 4
  • [ 28710-97-6 ]
  • [ 17422-74-1 ]
  • [ 1253038-69-5 ]
  • 5
  • [ 17422-74-1 ]
  • [ 4865-84-3 ]
  • 3-(((E)-2-benzo[d]isoxazol-3-yl)vinyl)-4H-chromen-4-one [ No CAS ]
  • 6
  • [ 13612-34-5 ]
  • [ 17422-74-1 ]
  • (E)-3-(2,5-dimethylstyryl)-4H-chromen-4-one [ No CAS ]
  • 7
  • [ 17422-74-1 ]
  • [ 145689-41-4 ]
  • (E)-3-(2,3-difluorostyryl)-4H-chromen-4-one [ No CAS ]
  • 8
  • [ 770-05-8 ]
  • [ 17422-74-1 ]
  • C18H15NO4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
37.6% With triethylamine; In methanol; In total, 1 mmol of <strong>[770-05-8]octopamine hydrochloride</strong>, 1 mmol triethylamine, and 1 mmol of chromone-3-carboxaldehyde were dissolved in 5 mL of MeOH. The reaction solution was stirred until white powder was formed, and the resulting powder was filtered and washed with acetone and ether. Yield: 116.3 mg (37.6%). 1H NMR (400 MHz in DMSO-d6, 20C): delta = 10.24 (s, 1H), delta = 9.30(s, 1H), delta = 7.77 (d, J = 8.1 Hz, 1H), delta = 7.44 (t,J = 8.2 Hz, 1H), delta = 7.31 (d, J = 12 Hz, 1H), delta = 7.18 (d,J = 8.2 Hz, 2H), delta = 7.05 (m, 2H), delta = 6.73 (d, J = 8 Hz,2H), delta = 5.63 (s, 1H), delta = 5.55 (t, J = 8 Hz, 1H), delta = 4.59(m, 1H), 3.46 (m, 1H). 13C NMR (700 MHz in DMSO-d6, 20 C, ppm): delta = 177.91, 156.51, 154.86, 133.18, 127.09,125.24, 123.16, 121.48, 117.52, 114.81, 101.52, 99.27,71.52, 56.22, 54.41. ESI-MS for C18H15NO4 + H+, Calcd,310.11 (m/z); found, 309.92. Elemental analysis Calcd (%)for C18H15NO4 + CH3OH: C, 66.85; H, 5.61; N, 4.10%;found (%): C, 66.69; H, 5.61; N, 3.99%.
  • 9
  • [ 13667-12-4 ]
  • [ 17422-74-1 ]
  • 3-(2-(4-bromophenyl)-3-fluoro-1H-inden-1-yl)-4H-chromen-4-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
59% With boron trifluoride diethyl etherate; In dichloromethane; at 20℃; for 2h; General procedure: To a mixture of carbaldehyde 3 (0.172 mmol, 1.0 equiv) and alkyne 4 (0.172 mmol, 1.0 equiv) in CH2Cl2 (2 mL) was added BF3·OEt2 (0.43 mmol, 2.5 equiv) at room temperature. The mixture was stirred for the required time (monitored by TLC). After completion of the reaction, it was quenched with a few drops of sat. Na2S2O3 solution. The solvent was removed through vacuum and the residue was purified by silica gel column chromatography (petroleum ether/EtOAc, 4:1) to afford 6aa-6ah.
  • 10
  • [ 769-26-6 ]
  • [ 17422-74-1 ]
  • C20H18O [ No CAS ]
 

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