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Chemical Structure| 17595-85-6 Chemical Structure| 17595-85-6

Structure of 17595-85-6

Chemical Structure| 17595-85-6

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Product Details of [ 17595-85-6 ]

CAS No. :17595-85-6
Formula : C12H10O2S
M.W : 218.27
SMILES Code : O=C(OC)C1=CC=CC(C2=CC=CS2)=C1
MDL No. :MFCD06204245

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Application In Synthesis of [ 17595-85-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 17595-85-6 ]

[ 17595-85-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 17595-85-6 ]
  • [ 29886-63-3 ]
YieldReaction ConditionsOperation in experiment
93.4% With sodium hydroxide; water; In tetrahydrofuran; methanol; at 60℃; for 2.0h; To a solution of 2-(3-methoxycarbonylphenyl)thiophene (1.29 g) in methanol (15 ml) and tetrahydrofuran (5 ml) was added an aqueous solution of sodium hydroxide (1N, 8.87 ml) followed by stirring for 2 hours at 60 C. To the mixture was added hydrochloric acid (1N, 10 ml).. The resulting precipitate was collected by filtration and dried to give 2-(3-carboxyphenyl)thiophene (1.13 g, 93.4%).NMR (DMSO-d6, delta): 7.17 (1H, t, J=4.4 Hz), 7.5-7.7(3H, m), 7.87 (1H, d, J=7.8 Hz), 7.93 (1H, d, J=7.8 Hz), 8.15 (1H, s), 13.19 (1H, broad s) ESI-Mass m/z: 203 (M-1).
 

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