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Chemical Structure| 17647-70-0 Chemical Structure| 17647-70-0

Structure of 17647-70-0

Chemical Structure| 17647-70-0

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Product Details of [ 17647-70-0 ]

CAS No. :17647-70-0
Formula : C3H5N3O
M.W : 99.09
SMILES Code : NC1=NON=C1C
MDL No. :MFCD00186403
InChI Key :QIEJLLIYONRHBH-UHFFFAOYSA-N
Pubchem ID :28674

Safety of [ 17647-70-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 17647-70-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 17647-70-0 ]

[ 17647-70-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 17647-70-0 ]
  • [ 1396456-75-9 ]
  • [ 68957-94-8 ]
  • [ 1400399-86-1 ]
YieldReaction ConditionsOperation in experiment
63% With hydrogenchloride; dmap; triethylamine; In tetrahydrofuran; n-heptane; dichloromethane; 1. Synthesis of 4-chloro-3-methoxy-N-(4-methyl-1,2,5-oxadiazol-3-yl)-2,3-dihydro-1-benzothiophene-5-carboxamide 1,1-dioxide (table example No. 1928) 1.00 g (3.14 mmol) of 4-chloro-3-methoxy-2,3-dihydro-1-benzothiophene-5-carboxylic acid 1,1-dioxide and 0.33 g (3.15 mmol) of 4-methyl-1,2,5-oxadiazol-3-yl-amine were dissolved at room temperature (RT) in 35 ml of CH2Cl2, 3.02 g (4.74 mmol) of 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane 2,4,6-trioxide (50% solution in THF) were added and the mixture was stirred at RT for 1 h. Subsequently, 2.18 ml (15.64 mmol) of triethylamine and 75 mg (0.61 mmol) of 4-dimethylaminopyridine (DMAP) were added and the whole mixture was stirred at RT for 16 h. This was followed by washing with water and twice with 6N hydrochloric acid, drying of the organic phase over Na2SO4 and filtration with suction through silica gel, washing through with 1:2 heptane/ethyl acetate and concentration. Yield 708 mg (63%). 1H NMR (CDCl3): delta=2.44 (s, 3H), 3.53 (s, 3H), 3.57 (dd, 1H), 3.71 (d, 1H), 5.15 (d, 1H), 7.55 (d, 1H), 7.74 (d, 1H), 9.40 (s, 1H)
 

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Related Functional Groups of
[ 17647-70-0 ]

Amines

Chemical Structure| 156463-85-3

A684132 [156463-85-3]

4-Amino-1,2,5-oxadiazole-3-carbonitrile

Similarity: 0.82

Related Parent Nucleus of
[ 17647-70-0 ]

Oxadiazoles

Chemical Structure| 156463-85-3

A684132 [156463-85-3]

4-Amino-1,2,5-oxadiazole-3-carbonitrile

Similarity: 0.82