Name: 17873-01-7|Trimethoxy(p-tolyl)silane|95%
Brand: Ambeed
SKU: A698976
Price: 21.0 USD
Availability: InStock
Rating: 91 (28 reviews)

1
[ 14371-10-9 ]
[ 17873-01-7 ]
[ 92804-29-0 ]

Yield	Reaction Conditions	Operation in experiment
85%	With tetrabutyl ammonium fluoride; antimony(III) chloride; acetic acid In acetonitrile at 60℃; for 24h;

Reference： [1]Denmark, Scott E.; Amishiro, Nobuyoshi [Journal of Organic Chemistry, 2003, vol. 68, # 18, p. 6997 - 7003]

2
[ 5153-67-3 ]
[ 17873-01-7 ]
[ 1882-47-9 ]

Yield	Reaction Conditions	Operation in experiment
54%	With tetrabutyl ammonium fluoride; antimony(III) chloride; acetic acid In acetonitrile at 60℃; for 24h;

Reference： [1]Denmark, Scott E.; Amishiro, Nobuyoshi [Journal of Organic Chemistry, 2003, vol. 68, # 18, p. 6997 - 7003]

3
(E)-1-phenyl-2-buten-1-one [ No CAS ]
[ 17873-01-7 ]
[ 62557-95-3 ]

Yield	Reaction Conditions	Operation in experiment
47%	With tetrabutyl ammonium fluoride; antimony(III) chloride; acetic acid In acetonitrile at 60℃; for 34h;

Reference： [1]Denmark, Scott E.; Amishiro, Nobuyoshi [Journal of Organic Chemistry, 2003, vol. 68, # 18, p. 6997 - 7003]

4
[ 18402-83-0 ]
[ 17873-01-7 ]
[ 182482-48-0 ]

Yield	Reaction Conditions	Operation in experiment
81%	In 1,4-dioxane; water at 95℃; for 23h;

Reference： [1]Nishikata, Takashi; Yamamoto, Yasunori; Miyaura, Norio [Chemistry Letters, 2003, vol. 32, # 8, p. 752 - 753]

5
[ 626-55-1 ]
[ 17873-01-7 ]
[ 4423-09-0 ]

Yield	Reaction Conditions	Operation in experiment
92%	With sodium hydroxide at 135℃; for 24h;
81%	With sodium hydroxide at 60℃; for 9h;
71%	With N-[(4-chlorophenyl)(1-methyl-1H-imidazol-2-yl)methyl]aniline; tetrabutylammomium bromide; palladium diacetate; sodium hydroxide In water at 100℃; for 0.5h; Microwave irradiation; Sealed tube;

71%

With N-[(4-chlorophenyl)(1-methyl-1H-imidazol-2-yl)methyl]aniline; tetrabutylammomium bromide; palladium diacetate; sodium hydroxide In neat (no solvent) at 100℃; for 0.5h; Microwave irradiation;

Reference： [1]Wolf, Christian; Lerebours, Rachel [Organic Letters, 2004, vol. 6, # 7, p. 1147 - 1150]
[2]Shi, Shengyin; Zhang, Yuhong [Journal of Organic Chemistry, 2007, vol. 72, # 15, p. 5927 - 5930]
[3]Martinez, Regina; Pastor, Isidro M.; Yus, Miguel [European Journal of Organic Chemistry, 2014, vol. 2014, # 4, p. 872 - 877]
[4]Martínez, Regina; Pastor, Isidro M.; Yus, Miguel [European Journal of Organic Chemistry, 2014, vol. 2014, # 4, p. 872 - 877]

6
[ 108-86-1 ]
[ 17873-01-7 ]
[ 644-08-6 ]

Yield	Reaction Conditions	Operation in experiment
96%	With N-methyliminodiacetic acid; sodium fluoride; potassium hydroxide; palladium dichloride In water; isopropyl alcohol at 80℃; for 6h;
86%	With 1,4-diaza-bicyclo[2.2.2]octane; tetrabutyl ammonium fluoride In 1,4-dioxane at 80℃; for 4h;
73%	With sodium hydroxide at 60℃; for 8h;

68 %Spectr.

With tetrabutyl-ammonium chloride; sodium hydroxide In water at 80℃; for 3h;

General Procedure for Hiyama Coupling Reaction (Table 1) General procedure: To a screw-capped vial with a stirring bar were added 4-bromotoluene(86.4 mg, 0.5 mmol), phenyltrimethoxysilane (152 mg,0.75 mmol), PS-PdONPs (2.9 mg, 1.5 mol% of Pd), TBAC (142 mg,0.5 mmol), and aq NaOH solution (1.5 M, 1 mL). After stirring at80 °C for 3 h, the reaction mixture was cooled to r.t. by immediatelyimmersing the vial in H2O (ca. 20 °C) for about 10 min.After separating the catalyst and the aqueous phase by centrifugation,the aqueous phase was decanted. The recovered catalystwas washed with H2O (5 × 3.0 mL) and Et2O (5 × 3.0 mL), whichwere then added to the aqueous phase. The aqueous phase wasextracted eight times with Et2O. The combined organic extractswere dried over MgSO4 and concentrated under reduced pressure.The product was analyzed by 1H NMR. The recovered catalystwas dried in vacuo and reused. Furthermore, the amount ofPd metal in the aqueous phase determined by ICP-AES analysiswas <0.1 ppm.

Reference： [1]Guo, Mengping; Qi, Liang; Zhang, Qiaochu; Zhu, Zhiyong; Li, Wei; Li, Xiaogang [Organic and Biomolecular Chemistry, 2014, vol. 12, # 36, p. 7136 - 7139]
[2]Li, Jin-Heng; Deng, Chen-Liang; Liu, Wen-Jie; Xie, Ye-Xiang [Synthesis, 2005, # 18, p. 3039 - 3044]
[3]Shi, Shengyin; Zhang, Yuhong [Journal of Organic Chemistry, 2007, vol. 72, # 15, p. 5927 - 5930]
[4]Ohtaka, Atsushi; Kotera, Takamasa; Sakon, Akira; Ueda, Kouhei; Hamasaka, Go; Uozumi, Yasuhiro; Shinagawa, Tsutomu; Shimomura, Osamu; Nomura, Ryôki [Synlett, 2016, vol. 27, # 8, p. 1202 - 1206]

7
[ 104-92-7 ]
[ 17873-01-7 ]
[ 53040-92-9 ]

Yield	Reaction Conditions	Operation in experiment
83%	With tetrabutyl ammonium fluoride; tris-(o-tolyl)phosphine at 80℃; for 0.75h;
78%	With N-[(4-chlorophenyl)(1-methyl-1H-imidazol-2-yl)methyl]aniline; tetrabutylammomium bromide; palladium diacetate; sodium hydroxide In water at 100℃; for 0.5h; Microwave irradiation; Sealed tube;
78%	With N-[(4-chlorophenyl)(1-methyl-1H-imidazol-2-yl)methyl]aniline; tetrabutylammomium bromide; palladium diacetate; sodium hydroxide In neat (no solvent) at 100℃; for 0.5h; Microwave irradiation;

70%	With 1,4-diaza-bicyclo[2.2.2]octane; tetrabutyl ammonium fluoride In 1,4-dioxane at 80℃; for 4h;
62%	With N-methyliminodiacetic acid; sodium fluoride; potassium hydroxide; palladium dichloride In water; isopropyl alcohol at 80℃; for 12h;

Reference： [1]Li, Jin-Heng; Deng, Chen-Liang; Xie, Ye-Xiang [Synthesis, 2006, # 6, p. 969 - 974]
[2]Martinez, Regina; Pastor, Isidro M.; Yus, Miguel [European Journal of Organic Chemistry, 2014, vol. 2014, # 4, p. 872 - 877]
[3]Martínez, Regina; Pastor, Isidro M.; Yus, Miguel [European Journal of Organic Chemistry, 2014, vol. 2014, # 4, p. 872 - 877]
[4]Li, Jin-Heng; Deng, Chen-Liang; Liu, Wen-Jie; Xie, Ye-Xiang [Synthesis, 2005, # 18, p. 3039 - 3044]
[5]Guo, Mengping; Qi, Liang; Zhang, Qiaochu; Zhu, Zhiyong; Li, Wei; Li, Xiaogang [Organic and Biomolecular Chemistry, 2014, vol. 12, # 36, p. 7136 - 7139]

8
[ 106-38-7 ]
[ 17873-01-7 ]
[ 613-33-2 ]

Reference： [1]Journal of Organic Chemistry,2007,vol. 72,p. 5927 - 5930
[2]Asian Journal of Chemistry,2014,vol. 26,p. 1015 - 1018
[3]Synthesis,2005,p. 3039 - 3044
[4]Synthesis,2006,p. 969 - 974
[5]Organic and Biomolecular Chemistry,2014,vol. 12,p. 7136 - 7139

9
[ 17873-01-7 ]
[ 100-00-5 ]
[ 2143-88-6 ]

Yield	Reaction Conditions	Operation in experiment
98%	With tetrabutyl ammonium fluoride; tris-(o-tolyl)phosphine at 80℃; for 0.666667h;
88%	With 1,4-diaza-bicyclo[2.2.2]octane; tetrabutyl ammonium fluoride In 1,4-dioxane at 80℃; for 12h;
84%	With NHC-Pd(II)-Im; tetrabutyl ammonium fluoride In toluene at 120℃; for 3h; Inert atmosphere;	2.2. General procedure for the NHC-Pd(II)-Im complex 1 catalyzed Hiyama reaction of aryl chlorides with aryltrimethoxysilanes General procedure: Under N2 atmosphere, NHC-Pd(II)-Im 1 (1.0 mol%), dry toluene (2.0 mL), aryl chlorides 2 (0.81 mmol), aryltrimethoxysilanes 3 (2.0 equiv) and TBAF•3H2O (2.0 equiv) were successively added into a Schlenk reaction tube. Then the tube was placed in a 120 °C oil bath and stirred for 3 h. The mixture was then allowed to cool to room temperature, diluted with ethyl acetate and washed with brine, dried over anhydrous Na2SO4, concentrated in vacuo and then purified by flash chromatography to give the pure products 4.

Reference： [1]Li, Jin-Heng; Deng, Chen-Liang; Xie, Ye-Xiang [Synthesis, 2006, # 6, p. 969 - 974]
[2]Li, Jin-Heng; Deng, Chen-Liang; Liu, Wen-Jie; Xie, Ye-Xiang [Synthesis, 2005, # 18, p. 3039 - 3044]
[3]Location in patent: experimental part Gu, Zheng-Song; Shao, Li-Xiong; Lu, Jian-Mei [Journal of Organometallic Chemistry, 2012, vol. 700, p. 132 - 134]

10
[ 17873-01-7 ]
[ 586-78-7 ]
[ 2143-88-6 ]

Yield	Reaction Conditions	Operation in experiment
95%	With 1,4-diaza-bicyclo[2.2.2]octane; tetrabutyl ammonium fluoride In 1,4-dioxane at 80℃; for 4h;
90%	With sodium hydroxide at 60℃; for 2h;

Reference： [1]Li, Jin-Heng; Deng, Chen-Liang; Liu, Wen-Jie; Xie, Ye-Xiang [Synthesis, 2005, # 18, p. 3039 - 3044]
[2]Shi, Shengyin; Zhang, Yuhong [Journal of Organic Chemistry, 2007, vol. 72, # 15, p. 5927 - 5930]

11
[ 917086-20-5 ]
[ 17873-01-7 ]
(2R,7aS)-2-(4-Methyl-benzyl)-hexahydro-pyrrolizin-3-one [ No CAS ]
(2S,7S)-2-(4-methylbenzyl)-hexahydropyrrolizin-3-one [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
76%	In 1,4-dioxane; water at 110℃; for 24h;

Reference： [1]Hargrave, Jonathan D.; Bish, Gerwyn; Frost, Christopher G. [Chemical Communications, 2006, # 42, p. 4389 - 4391]

12
[ 930-68-7 ]
[ 17873-01-7 ]
[ 99495-15-5 ]

Yield	Reaction Conditions	Operation in experiment
91%	With tetrakis(actonitrile)copper(I) hexafluorophosphate; water at 120℃; for 4h; microwave irradiation;

Reference： [1]Lerebours, Rachel; Wolf, Christian [Organic Letters, 2007, vol. 9, # 14, p. 2737 - 2740]

13
[ 51-17-2 ]
[ 17873-01-7 ]
[ 60057-83-2 ]

Yield	Reaction Conditions	Operation in experiment
93%	With tetrabutyl ammonium fluoride; iron(III) chloride; copper at 50℃; for 24h;

Reference： [1]Song, Ren-Jie; Deng, Chen-Liang; Xie, Ye-Xiang; Li, Jin-Heng [Tetrahedron Letters, 2007, vol. 48, # 44, p. 7845 - 7848]

14
[ 288-32-4 ]
[ 17873-01-7 ]
[ 25372-10-5 ]

Yield	Reaction Conditions	Operation in experiment
58%	With tetrabutyl ammonium fluoride; iron(III) chloride; copper at 50℃; for 24h;

Reference： [1]Song, Ren-Jie; Deng, Chen-Liang; Xie, Ye-Xiang; Li, Jin-Heng [Tetrahedron Letters, 2007, vol. 48, # 44, p. 7845 - 7848]

15
[ 288-88-0 ]
[ 17873-01-7 ]
[ 2244-88-4 ]

Yield	Reaction Conditions	Operation in experiment
96%	With tetrabutyl ammonium fluoride; iron(III) chloride; copper at 50℃; for 24h;

Reference： [1]Song, Ren-Jie; Deng, Chen-Liang; Xie, Ye-Xiang; Li, Jin-Heng [Tetrahedron Letters, 2007, vol. 48, # 44, p. 7845 - 7848]

16
[ 288-36-8 ]
[ 17873-01-7 ]
[ 20320-18-7 ]

Yield	Reaction Conditions	Operation in experiment
57%	With tetrabutyl ammonium fluoride; iron(III) chloride; copper at 50℃; for 24h;

Reference： [1]Song, Ren-Jie; Deng, Chen-Liang; Xie, Ye-Xiang; Li, Jin-Heng [Tetrahedron Letters, 2007, vol. 48, # 44, p. 7845 - 7848]

17
6Pd⁽²⁺⁾*6(C₅H₄N)2*4C₃N₃(C₅H₄N)3*12NO₃^(1-)=Pd₆((C₅H₄N)2)6(C₃N₃(C₅H₄N)3)4(NO₃)12 [ No CAS ]
[ 17873-01-7 ]
6Pd⁽²⁺⁾*6C₁₀N₂H₈*4C₃N₃(C₅NH₄)3*12NO₃^(1-)*(SiOOHC₆H₄CH₃)3=(Pd(C₅H₄N)4)6(C₃N₃)4(NO₃)12*(SiOOHC₆H₄CH₃)3 [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
90%	In water silan suspended in aq. soln. of host at 100 °C, mixt. stirred for100 °C for 1 h; mixt. cooled to room temp., soln. filtered, evapd., product recrystd. from H2O; detnd. by XRD, NMR;

Reference： [1]Kusukawa, Takahiro; Yoshizawa, Michito; Fujita, Makoto [Angewandte Chemie - International Edition, 2001, vol. 40, # 10, p. 1879 - 1884]

18
[ 1016624-90-0 ]
[ 17873-01-7 ]
[ 1016627-44-3 ]
[ 1016627-28-3 ]

Yield	Reaction Conditions	Operation in experiment
	With (1,2-dimethoxyethane)dichloronickel(II) In 1,4-dioxane at 20℃; for 16h; Title compound not separated from byproducts.;
	With (1,2-dimethoxyethane)dichloronickel(II) In 1,4-dioxane at 20℃; for 16h; Title compound not separated from byproducts.;

Reference： [1]Dai, Xing; Strotman, Neil A.; Fu, Gregory C. [Journal of the American Chemical Society, 2008, vol. 130, # 11, p. 3302 - 3303]
[2]Dai, Xing; Strotman, Neil A.; Fu, Gregory C. [Journal of the American Chemical Society, 2008, vol. 130, # 11, p. 3302 - 3303]

19
C₁₇H₁₉O₄SN [ No CAS ]
[ 17873-01-7 ]
4-(4'-methylbiphenyl-3-yl)morpholine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
81%	With dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl; tetrabutyl ammonium fluoride; palladium diacetate In tetrahydrofuran at 80℃; Inert atmosphere;

Reference： [1]Zhang, Liang; Wu, Jie [Journal of the American Chemical Society, 2008, vol. 130, # 37, p. 12250 - 12251]

20
[ 15161-04-3 ]
[ 17873-01-7 ]
[ 27331-34-6 ]

Yield	Reaction Conditions	Operation in experiment
63%	With dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl; tetrabutyl ammonium fluoride; palladium diacetate In tetrahydrofuran at 80℃; Inert atmosphere;

Reference： [1]Zhang, Liang; Wu, Jie [Journal of the American Chemical Society, 2008, vol. 130, # 37, p. 12250 - 12251]

21
[ 7385-85-5 ]
[ 17873-01-7 ]
[ 59115-49-0 ]

Yield	Reaction Conditions	Operation in experiment
78%	With dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl; tetrabutyl ammonium fluoride; palladium diacetate In tetrahydrofuran at 80℃; Inert atmosphere;

Reference： [1]Zhang, Liang; Wu, Jie [Journal of the American Chemical Society, 2008, vol. 130, # 37, p. 12250 - 12251]

22
[ 17873-01-7 ]
[ 536-74-3 ]
[ 3287-02-3 ]

Yield	Reaction Conditions	Operation in experiment
90%	With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; silver fluoride; sodium hydrogencarbonate In acetonitrile at 20℃; for 3h;

Reference： [1]Location in patent: scheme or table Ye, Zhishi; Liu, Miaochang; Lin, Baoda; Wu, Huayue; Ding, Jinchang; Cheng, Jiang [Tetrahedron Letters, 2009, vol. 50, # 5, p. 530 - 532]

23
[ 52843-75-1 ]
[ 17873-01-7 ]
[ 4423-09-0 ]

Yield	Reaction Conditions	Operation in experiment
40%	With tetrabutyl ammonium fluoride; palladium diacetate; XPhos In tetrahydrofuran; <i>tert</i>-butyl alcohol at 90℃; Inert atmosphere;

Reference： [1]Zhang, Liang; Qing, Jiang; Yang, Pengyuan; Wu, Jie [Organic Letters, 2008, vol. 10, # 21, p. 4971 - 4974]

24
[ 17873-01-7 ]
[ 52200-03-0 ]
[ 24423-07-2 ]

Yield	Reaction Conditions	Operation in experiment
96%	With tetrabutyl ammonium fluoride; palladium diacetate; XPhos In tetrahydrofuran; <i>tert</i>-butyl alcohol at 90℃; Inert atmosphere;

Reference： [1]Zhang, Liang; Qing, Jiang; Yang, Pengyuan; Wu, Jie [Organic Letters, 2008, vol. 10, # 21, p. 4971 - 4974]

25
[ 17873-01-7 ]
[ 59970-38-6 ]
1-(4-tert-butylphenyl)-4-methylbenzene [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
76%	With 2-[2-(dicyclohexylphosphino)-phenyl]-1-methyl-1H-indole; tetrabutyl ammonium fluoride; palladium diacetate; acetic acid In <i>tert</i>-butyl alcohol at 90℃; for 16h; Inert atmosphere;
71%	With tetrabutyl ammonium fluoride; palladium diacetate; XPhos In tetrahydrofuran; <i>tert</i>-butyl alcohol at 90℃; Inert atmosphere;

Reference： [1]So, Chau Ming; Lee, Hang Wai; Lau, Chak Po; Kwong, Fuk Yee [Organic Letters, 2009, vol. 11, # 2, p. 317 - 320]
[2]Zhang, Liang; Qing, Jiang; Yang, Pengyuan; Wu, Jie [Organic Letters, 2008, vol. 10, # 21, p. 4971 - 4974]

26
[ 1070731-22-4 ]
[ 17873-01-7 ]
[ 7383-87-1 ]

Yield	Reaction Conditions	Operation in experiment
84%	With 2-[2-(dicyclohexylphosphino)-phenyl]-1-methyl-1H-indole; tetrabutyl ammonium fluoride; palladium diacetate; acetic acid In <i>tert</i>-butyl alcohol at 90℃; for 16h; Inert atmosphere;

Reference： [1]So, Chau Ming; Lee, Hang Wai; Lau, Chak Po; Kwong, Fuk Yee [Organic Letters, 2009, vol. 11, # 2, p. 317 - 320]

27
[ 10290-91-2 ]
[ 17873-01-7 ]
[ 59115-49-0 ]

Yield	Reaction Conditions	Operation in experiment
71%	With 2-[2-(dicyclohexylphosphino)-phenyl]-1-methyl-1H-indole; tetrabutyl ammonium fluoride; palladium diacetate; acetic acid In <i>tert</i>-butyl alcohol at 90℃; for 16h; Inert atmosphere;

Reference： [1]So, Chau Ming; Lee, Hang Wai; Lau, Chak Po; Kwong, Fuk Yee [Organic Letters, 2009, vol. 11, # 2, p. 317 - 320]

28
[ 13141-42-9 ]
[ 17873-01-7 ]
C₂₀H₁₇N [ No CAS ]
C₂₀H₁₇N [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Stage #1: 2-(2-phenylethynyl)pyridine; (4-methylphenyl)trimethoxysilane With chloro(1,5-cyclooctadiene)rhodium(I) dimer; tetrabutyl ammonium fluoride; copper diacetate; triphenylphosphine In toluene at 20℃; for 2h; Stage #2: With water In toluene at 110℃; for 12h; regioselective reaction;

Reference： [1]Location in patent: experimental part Lin, Baoda; Liu, Miaochang; Ye, Zhishi; Zhang, Qin; Cheng, Jiang [Tetrahedron Letters, 2009, vol. 50, # 15, p. 1714 - 1716]

29
[ 1129-65-3 ]
[ 17873-01-7 ]
C₁₉H₂₂ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
88%	Stage #1: (hex-1-yn-1-yl)benzene; (4-methylphenyl)trimethoxysilane With chloro(1,5-cyclooctadiene)rhodium(I) dimer; tetrabutyl ammonium fluoride; copper diacetate; triphenylphosphine In toluene at 20℃; for 2h; Stage #2: With water In toluene at 110℃; for 12h; regioselective reaction;

Reference： [1]Location in patent: experimental part Lin, Baoda; Liu, Miaochang; Ye, Zhishi; Zhang, Qin; Cheng, Jiang [Tetrahedron Letters, 2009, vol. 50, # 15, p. 1714 - 1716]

30
[ 17873-01-7 ]
[ 501-65-5 ]
[ 70603-14-4 ]

Yield	Reaction Conditions	Operation in experiment
80%	Stage #1: (4-methylphenyl)trimethoxysilane; diphenyl acetylene With chloro(1,5-cyclooctadiene)rhodium(I) dimer; tetrabutyl ammonium fluoride; copper diacetate; triphenylphosphine In toluene at 20℃; for 2h; Stage #2: With water In toluene at 110℃; for 12h;

Reference： [1]Location in patent: experimental part Lin, Baoda; Liu, Miaochang; Ye, Zhishi; Zhang, Qin; Cheng, Jiang [Tetrahedron Letters, 2009, vol. 50, # 15, p. 1714 - 1716]

31
5-chloro-1-(4-methoxybenzyl)-3-(phenylsulfanyl)pyrazin-2(1H)-one [ No CAS ]
[ 17873-01-7 ]
5-chloro-3-(4-methylphenyl)-1-(4-methoxybenzyl)-2(1H)-pyrazinone [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
89%	With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutyl ammonium fluoride In tetrahydrofuran at 60℃; for 2h; Inert atmosphere;

Reference： [1]Mehta, Vaibhav Pravinchandra; Sharma, Anuj; Van Der Eycken, Erik [Advanced Synthesis and Catalysis, 2008, vol. 350, # 14-15, p. 2174 - 2178]

32
[ 17873-01-7 ]
[ 62-53-3 ]
[ 620-84-8 ]

Yield	Reaction Conditions	Operation in experiment
65%	Stage #1: (4-methylphenyl)trimethoxysilane With tetrabutyl ammonium fluoride; copper diacetate; tris(pentafluorophenyl)phosphine In dichloromethane; water at 20℃; for 0.0833333h; Molecular sieve; Stage #2: aniline With oxygen In dichloromethane; water at 20℃; for 24h;

Reference： [1]Lin, Baoda; Liu, Miaochang; Ye, Zhishi; Ding, Jinchang; Wu, Huayue; Cheng, Jiang [Organic and Biomolecular Chemistry, 2009, vol. 7, # 5, p. 869 - 873]

33
[ 109-09-1 ]
[ 17873-01-7 ]
[ 4467-06-5 ]

Yield	Reaction Conditions	Operation in experiment
83%	With tBu₂P-N=P(iBuPCH₂CH₂)3N; tetrabutyl ammonium fluoride; palladium diacetate at 80℃; for 2h; Inert atmosphere; Neat (no solvent);

Reference： [1]Raders, Steven M.; Kingston, Jesudoss V.; Verkade, John G. [Journal of Organic Chemistry, 2010, vol. 75, # 5, p. 1744 - 1747]

34
[ 2398-37-0 ]
[ 17873-01-7 ]
[ 24423-07-2 ]

Yield	Reaction Conditions	Operation in experiment
91%	With tBu₂P-N=P(iBuPCH₂CH₂)3N; tetrabutyl ammonium fluoride; palladium diacetate at 80℃; for 3h; Inert atmosphere; Neat (no solvent);

Reference： [1]Raders, Steven M.; Kingston, Jesudoss V.; Verkade, John G. [Journal of Organic Chemistry, 2010, vol. 75, # 5, p. 1744 - 1747]

35
[ 623-12-1 ]
[ 17873-01-7 ]
[ 53040-92-9 ]

Yield	Reaction Conditions	Operation in experiment
82%	With tBu₂P-N=P(iBuPCH₂CH₂)3N; tetrabutyl ammonium fluoride; palladium diacetate at 80℃; for 2h; Inert atmosphere; Neat (no solvent);
82%	With 3-(dicyclohexylphosphino)-2-(2-methoxyphenyl)-1-methyl-1-H-indole; tetrabutyl ammonium fluoride; palladium diacetate at 110℃; for 3h; Schlenk technique; Inert atmosphere; Sealed tube;

Reference： [1]Raders, Steven M.; Kingston, Jesudoss V.; Verkade, John G. [Journal of Organic Chemistry, 2010, vol. 75, # 5, p. 1744 - 1747]
[2]Yuen, On Ying; So, Chau Ming; Man, Ho Wing; Kwong, Fuk Yee [Chemistry - A European Journal, 2016, vol. 22, # 19, p. 6471 - 6476]

36
[ 98-81-7 ]
[ 17873-01-7 ]
[ 948-55-0 ]

Yield	Reaction Conditions	Operation in experiment
78%	With tBu₂P-N=P(iBuPCH₂CH₂)3N; tetrabutyl ammonium fluoride; palladium diacetate at 80℃; for 1h; Inert atmosphere; Neat (no solvent);

Reference： [1]Raders, Steven M.; Kingston, Jesudoss V.; Verkade, John G. [Journal of Organic Chemistry, 2010, vol. 75, # 5, p. 1744 - 1747]

37
[ 586-77-6 ]
[ 17873-01-7 ]
[ 141082-00-0 ]

Yield	Reaction Conditions	Operation in experiment
71%	With tBu₂P-N=P(iBuPCH₂CH₂)3N; tetrabutyl ammonium fluoride; palladium diacetate In 1,4-dioxane at 80℃; for 5h; Inert atmosphere;

Reference： [1]Raders, Steven M.; Kingston, Jesudoss V.; Verkade, John G. [Journal of Organic Chemistry, 2010, vol. 75, # 5, p. 1744 - 1747]

38
[ 603-76-9 ]
[ 17873-01-7 ]
[ 51358-08-8 ]

Yield	Reaction Conditions	Operation in experiment
81%	With tetrabutyl ammonium fluoride; palladium diacetate; acetic acid; silver(l) oxide In tetrahydrofuran; ethanol at 20℃; Inert atmosphere; regioselective reaction;

Reference： [1]Liang, Zunjun; Yao, Bangben; Zhang, Yuhong [Organic Letters, 2010, vol. 12, # 14, p. 3185 - 3187]

39
[ 930-68-7 ]
[ 17873-01-7 ]
[ 6330-12-7 ]

Yield	Reaction Conditions	Operation in experiment
82%	With 1,10-Phenanthroline; palladium diacetate; silver fluoride In N,N-dimethyl-formamide at 60℃;

Reference： [1]Ye, Zhishi; Chen, Fan; Luo, Fang; Wang, Wenhui; Lin, Baoda; Jia, Xiaofei; Cheng, Jiang [Synlett, 2009, # 13, p. 2198 - 2200]

40
[ 1008-89-5 ]
[ 17873-01-7 ]
2-[4’-methyl-(1,1’-biphenyl)-2-yl]pyridine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
63%	With palladium diacetate; silver fluoride; p-benzoquinone In 1,4-dioxane at 110℃; for 24h; Inert atmosphere; seal tube;
67 %Chromat.	With copper (II)-fluoride; silver hexafluoroantimonate; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂ In 1,2-dichloro-ethane at 140℃; for 20h; Inert atmosphere;

Reference： [1]Location in patent: experimental part Li, Wu; Yin, Zhangwei; Jiang, Xiaoqing; Sun, Peipei [Journal of Organic Chemistry, 2011, vol. 76, # 20, p. 8543 - 8548]
[2]Nareddy, Pradeep; Jordan, Frank; Szostak, Michal [Organic and Biomolecular Chemistry, 2017, vol. 15, # 22, p. 4783 - 4788]

41
[ 17873-01-7 ]
[ 106-49-0 ]
[ 613-33-2 ]

Yield	Reaction Conditions	Operation in experiment
		General procedure: The concentration of0.25mol aniline was dissolved in the mixture of 63 ml HCl and 63 ml water in600 ml beaker. After cooled to 0-5 oC with stirring, anilinehydrochloride crystallization. Aqueous solution of sodium nitrite (18gdissolved in 40 ml water) was added into beaker dropwise with stirring, keepingthe temperature under 5 oC. 40 g of sodium tetrafluoroboratesolution dissolved in 80 ml water was added to the diazonium salt solution, andthen continue to stir for 10 minutes. The solid was immediately washed by 10 ml5 % solution of sodium tetrafluoroborate for three times after filtered, andthen washed by 15 ml methanol twice to afford diazonium salt.A mixture of arenediazonium tetrafluoroborate salt(0.5 mmol), Pd(OAc)2 (5 mol%), TBAF (0.5 mmol) and aryl silanes (0.6mmol) was stirred in water (1 mL) at room termperature for 6 h. Afterwards, thereaction solution was filtered through a filter paper and the solution wasextracted by Et2O (1 mL) for three times. The organic phase wascombined and evaporated under reduced pressure. The residue was purified on aSiO2 column to afford the desired product.

Reference： [1]Journal of Organic Chemistry,2011,vol. 76,p. 9261 - 9268
[2]Tetrahedron Letters,2013,vol. 54,p. 6211 - 6214

42
[ 141-32-2 ]
[ 17873-01-7 ]
[ 123248-21-5 ]

Yield	Reaction Conditions	Operation in experiment
70%	With tetrabutyl ammonium fluoride; p-benzoquinone In tetrahydrofuran at 40℃; for 14h;
60%	With C₁₄H₁₆N₆; palladium diacetate; silver fluoride In N,N-dimethyl acetamide at 60℃; for 24h;	4.3. General procedure of palladium-catalyzed Mizoroki-Heck type reaction with aryl trialkoxysilanesCommentComment General procedure: To a mixture of olefin (0.5 mmol), AgF (0.191 mg, 1.5 mmol), Pd(OAc)2 (5.6 mg, 25 μmol), and ligand 1e (6.7 mg, 25 μmol) in DMAc (1.0 mL) was added aryl trialkoxysilane (1.0 mmol) at room temperature under an atmosphere of air. The mixture was stirred at 60 °C. After 24 h, the mixture was diluted with ethyl acetate and water. The organic layer was washed with brine, dried over MgSO4, and concentrated under reduced pressure. The residue was purified by silica gel chromatography (hexane or hexane/EtOAc=100 to 10/1).

Reference： [1]Patra, Debabrata; Panja, Subir; Saha, Amit [European Journal of Organic Chemistry, 2020, vol. 2020, # 7, p. 878 - 883]
[2]Location in patent: experimental part Mino, Takashi; Shibuya, Masanori; Suzuki, Saori; Hirai, Kiminori; Sakamoto, Masami; Fujita, Tsutomu [Tetrahedron, 2012, vol. 68, # 2, p. 429 - 432]

43
[ 17873-01-7 ]
[ 99-90-1 ]
[ 5748-38-9 ]

Yield	Reaction Conditions	Operation in experiment
46%	With 3-benzyl-1-(2-hydroxy-2-phenylethyl)imidazolium chloride; water; palladium diacetate; sodium hydroxide at 120℃; for 1h; Microwave irradiation;

Reference： [1]Location in patent: experimental part Penafiel, Itziar; Pastor, Isidro M.; Yus, Miguel; Esteruelas, Miguel A.; Olivan, Montserrat; Onate, Enrique [European Journal of Organic Chemistry, 2011, # 35, p. 7174 - 7181]

44
[ 623-03-0 ]
[ 17873-01-7 ]
[ 50670-50-3 ]

Yield	Reaction Conditions	Operation in experiment
81%	With NHC-Pd(II)-Im; tetrabutyl ammonium fluoride In toluene at 120℃; for 3h; Inert atmosphere;	2.2. General procedure for the NHC-Pd(II)-Im complex 1 catalyzed Hiyama reaction of aryl chlorides with aryltrimethoxysilanes General procedure: Under N2 atmosphere, NHC-Pd(II)-Im 1 (1.0 mol%), dry toluene (2.0 mL), aryl chlorides 2 (0.81 mmol), aryltrimethoxysilanes 3 (2.0 equiv) and TBAF•3H2O (2.0 equiv) were successively added into a Schlenk reaction tube. Then the tube was placed in a 120 °C oil bath and stirred for 3 h. The mixture was then allowed to cool to room temperature, diluted with ethyl acetate and washed with brine, dried over anhydrous Na2SO4, concentrated in vacuo and then purified by flash chromatography to give the pure products 4.

Reference： [1]Location in patent: experimental part Gu, Zheng-Song; Shao, Li-Xiong; Lu, Jian-Mei [Journal of Organometallic Chemistry, 2012, vol. 700, p. 132 - 134]

45
[ 1126-46-1 ]
[ 17873-01-7 ]
[ 49742-56-5 ]

Yield	Reaction Conditions	Operation in experiment
79%	With NHC-Pd(II)-Im; tetrabutyl ammonium fluoride In toluene at 120℃; for 3h; Inert atmosphere;	2.2. General procedure for the NHC-Pd(II)-Im complex 1 catalyzed Hiyama reaction of aryl chlorides with aryltrimethoxysilanes General procedure: Under N2 atmosphere, NHC-Pd(II)-Im 1 (1.0 mol%), dry toluene (2.0 mL), aryl chlorides 2 (0.81 mmol), aryltrimethoxysilanes 3 (2.0 equiv) and TBAF•3H2O (2.0 equiv) were successively added into a Schlenk reaction tube. Then the tube was placed in a 120 °C oil bath and stirred for 3 h. The mixture was then allowed to cool to room temperature, diluted with ethyl acetate and washed with brine, dried over anhydrous Na2SO4, concentrated in vacuo and then purified by flash chromatography to give the pure products 4.

Reference： [1]Location in patent: experimental part Gu, Zheng-Song; Shao, Li-Xiong; Lu, Jian-Mei [Journal of Organometallic Chemistry, 2012, vol. 700, p. 132 - 134]

46
[ 17873-01-7 ]
[ 99-91-2 ]
[ 5748-38-9 ]

Yield	Reaction Conditions	Operation in experiment
73%	With NHC-Pd(II)-Im; tetrabutyl ammonium fluoride In toluene at 120℃; for 3h; Inert atmosphere;	2.2. General procedure for the NHC-Pd(II)-Im complex 1 catalyzed Hiyama reaction of aryl chlorides with aryltrimethoxysilanes General procedure: Under N2 atmosphere, NHC-Pd(II)-Im 1 (1.0 mol%), dry toluene (2.0 mL), aryl chlorides 2 (0.81 mmol), aryltrimethoxysilanes 3 (2.0 equiv) and TBAF•3H2O (2.0 equiv) were successively added into a Schlenk reaction tube. Then the tube was placed in a 120 °C oil bath and stirred for 3 h. The mixture was then allowed to cool to room temperature, diluted with ethyl acetate and washed with brine, dried over anhydrous Na2SO4, concentrated in vacuo and then purified by flash chromatography to give the pure products 4.

Reference： [1]Location in patent: experimental part Gu, Zheng-Song; Shao, Li-Xiong; Lu, Jian-Mei [Journal of Organometallic Chemistry, 2012, vol. 700, p. 132 - 134]

47
[ 624-31-7 ]
[ 17873-01-7 ]
[ 613-33-2 ]

Yield	Reaction Conditions	Operation in experiment
80%	With tetrabutyl ammonium fluoride; In water; toluene; at 100℃; for 20h;	General procedure: Catalyst 1a22a (43 mg, 0.1 mol % of supported palladium) was added to a solution of aryl iodide (0.40 mmol, 1.0 equiv), aryltrialkoxysilane (0.80 mmol, 2.0 equiv), TBAF·3H2O (252 mg, 0.8 mmol, 2.0 equiv) in a mixture of toluene (5 mL) and H2O (50 muL). The reaction mixture was heated at 100 C for 20 h. After cooling to rt, 1a was filtered under vacuum on a 0.2 mum membrane. The catalyst was successively washed with toluene (10 mL) and Et2O (10 mL). The combined organic phases were washed with H2O (20 mL), dried with MgSO4, filtered, and concentrated under vacuum. The residue was purified by flash-chromatography on silica gel. Catalyst 1a was dried under vacuum and can directly be used for another Hiyama coupling.

Reference： [1]Tetrahedron,2013,vol. 69,p. 264 - 267

48
AuOH(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) [ No CAS ]
[ 17873-01-7 ]
[N,N'-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](4-tolyldimethoxysilanolate)gold(I) [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
99%	With air In toluene at 20℃; for 1h; Inert atmosphere;

Reference： [1]Dupuy, Stéphanie; Slawin, Alexandra M. Z.; Nolan, Steven P. [Chemistry - A European Journal, 2012, vol. 18, # 47, p. 14923 - 14928]

49
AuOH(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) [ No CAS ]
[ 17873-01-7 ]
(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)(p-methylphenyl)gold [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
94%	In 1,4-dioxane at 110℃; for 0.8h; Inert atmosphere;

Reference： [1]Dupuy, Stéphanie; Slawin, Alexandra M. Z.; Nolan, Steven P. [Chemistry - A European Journal, 2012, vol. 18, # 47, p. 14923 - 14928]

50
[ 17873-01-7 ]
[ 824-79-3 ]
[ 613-33-2 ]

Reference： [1]Journal of Organic Chemistry,2013,vol. 78,p. 5022 - 5025

51
[ 17873-01-7 ]
[ 613-33-2 ]

Reference： [1]Synthetic Communications,2013,vol. 43,p. 2733 - 2738

52
[ 3972-65-4 ]
[ 17873-01-7 ]
1-(4-tert-butylphenyl)-4-methylbenzene [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
80%	With N-[(4-chlorophenyl)(1-methyl-1H-imidazol-2-yl)methyl]aniline; tetrabutylammomium bromide; palladium diacetate; sodium hydroxide In water at 100℃; for 0.5h; Microwave irradiation; Sealed tube;
80%	With N-[(4-chlorophenyl)(1-methyl-1H-imidazol-2-yl)methyl]aniline; tetrabutylammomium bromide; palladium diacetate; sodium hydroxide In neat (no solvent) at 100℃; for 0.5h; Microwave irradiation;

Reference： [1]Martinez, Regina; Pastor, Isidro M.; Yus, Miguel [European Journal of Organic Chemistry, 2014, vol. 2014, # 4, p. 872 - 877]
[2]Martínez, Regina; Pastor, Isidro M.; Yus, Miguel [European Journal of Organic Chemistry, 2014, vol. 2014, # 4, p. 872 - 877]

53
[ 95-46-5 ]
[ 17873-01-7 ]
[ 611-61-0 ]

Yield	Reaction Conditions	Operation in experiment
82%	With N-[(4-chlorophenyl)(1-methyl-1H-imidazol-2-yl)methyl]aniline; tetrabutylammomium bromide; palladium diacetate; sodium hydroxide In water at 100℃; for 0.5h; Microwave irradiation; Sealed tube;
82%	With N-[(4-chlorophenyl)(1-methyl-1H-imidazol-2-yl)methyl]aniline; tetrabutylammomium bromide; palladium diacetate; sodium hydroxide In neat (no solvent) at 100℃; for 0.5h; Microwave irradiation;

Reference： [1]Martinez, Regina; Pastor, Isidro M.; Yus, Miguel [European Journal of Organic Chemistry, 2014, vol. 2014, # 4, p. 872 - 877]
[2]Martínez, Regina; Pastor, Isidro M.; Yus, Miguel [European Journal of Organic Chemistry, 2014, vol. 2014, # 4, p. 872 - 877]

54
[ 1483-82-5 ]
[ 17873-01-7 ]
[ 3287-02-3 ]

Yield	Reaction Conditions	Operation in experiment
90%	With silver fluoride; potassium hydrogencarbonate; bis(dibenzylideneacetone)-palladium⁽⁰⁾ In acetonitrile at 20℃; for 12h;	Synthesis of internal alkynes (3-12); general procedure General procedure: Alkynyl halide 1 (0.2 mmol), aryltrialkoxysilane 2 (0.4 mmol), Pd(dba)2 (3 mol %), AgF (3 equiv.), KHCO3 (2 equiv.), all values compared to 1, and MeCN (2 mL) were added to a Schlenk tube in turn. Then the solution was stirred at room temperature for the indicated time (usually 12 h) until complete consumption of starting material as monitored by TLC and GC-MS analysis. Afterthe reaction was finished, the crude reaction mixture was filtered, poured into diethyl ether (10 mL), washed with brine (3 mL × 3), extracted with diethyl ether (5 mL × 3), dried over anhydrous Na2SO4, and evaporated under reduced pressure. The residue was purified by flash column chromatography on silica gel (hexane/ethyl acetate) to afford the desired product.

Reference： [1]Tang, Jiansheng; Guo, Cancheng [Journal of Chemical Research, 2014, vol. 38, # 2, p. 123 - 127]

55
[ 932-88-7 ]
[ 17873-01-7 ]
[ 886-66-8 ]
[ 3287-02-3 ]

Yield	Reaction Conditions	Operation in experiment
1: 40% 2: 33 %Chromat.	With silver fluoride; potassium hydrogencarbonate; bis(dibenzylideneacetone)-palladium⁽⁰⁾ In acetonitrile at 20℃; for 12h;	Synthesis of internal alkynes (3-12); general procedure General procedure: Alkynyl halide 1 (0.2 mmol), aryltrialkoxysilane 2 (0.4 mmol), Pd(dba)2 (3 mol %), AgF (3 equiv.), KHCO3 (2 equiv.), all values compared to 1, and MeCN (2 mL) were added to a Schlenk tube in turn. Then the solution was stirred at room temperature for the indicated time (usually 12 h) until complete consumption of starting material as monitored by TLC and GC-MS analysis. Afterthe reaction was finished, the crude reaction mixture was filtered, poured into diethyl ether (10 mL), washed with brine (3 mL × 3), extracted with diethyl ether (5 mL × 3), dried over anhydrous Na2SO4, and evaporated under reduced pressure. The residue was purified by flash column chromatography on silica gel (hexane/ethyl acetate) to afford the desired product.

Reference： [1]Tang, Jiansheng; Guo, Cancheng [Journal of Chemical Research, 2014, vol. 38, # 2, p. 123 - 127]

56
[ 19821-84-2 ]
[ 17873-01-7 ]
[ 121866-33-9 ]

Yield	Reaction Conditions	Operation in experiment
44%	With silver fluoride; potassium hydrogencarbonate; bis(dibenzylideneacetone)-palladium⁽⁰⁾ In acetonitrile at 20℃; for 12h;	Synthesis of internal alkynes (3-12); general procedure General procedure: Alkynyl halide 1 (0.2 mmol), aryltrialkoxysilane 2 (0.4 mmol), Pd(dba)2 (3 mol %), AgF (3 equiv.), KHCO3 (2 equiv.), all values compared to 1, and MeCN (2 mL) were added to a Schlenk tube in turn. Then the solution was stirred at room temperature for the indicated time (usually 12 h) until complete consumption of starting material as monitored by TLC and GC-MS analysis. Afterthe reaction was finished, the crude reaction mixture was filtered, poured into diethyl ether (10 mL), washed with brine (3 mL × 3), extracted with diethyl ether (5 mL × 3), dried over anhydrous Na2SO4, and evaporated under reduced pressure. The residue was purified by flash column chromatography on silica gel (hexane/ethyl acetate) to afford the desired product.

Reference： [1]Tang, Jiansheng; Guo, Cancheng [Journal of Chemical Research, 2014, vol. 38, # 2, p. 123 - 127]

57
[ 17873-01-7 ]
[ 932-87-6 ]
[ 3287-02-3 ]

Yield	Reaction Conditions	Operation in experiment
83%	With silver fluoride; potassium hydrogencarbonate; bis(dibenzylideneacetone)-palladium⁽⁰⁾ In acetonitrile at 20℃; for 12h;	Synthesis of internal alkynes (3-12); general procedure General procedure: Alkynyl halide 1 (0.2 mmol), aryltrialkoxysilane 2 (0.4 mmol), Pd(dba)2 (3 mol %), AgF (3 equiv.), KHCO3 (2 equiv.), all values compared to 1, and MeCN (2 mL) were added to a Schlenk tube in turn. Then the solution was stirred at room temperature for the indicated time (usually 12 h) until complete consumption of starting material as monitored by TLC and GC-MS analysis. Afterthe reaction was finished, the crude reaction mixture was filtered, poured into diethyl ether (10 mL), washed with brine (3 mL × 3), extracted with diethyl ether (5 mL × 3), dried over anhydrous Na2SO4, and evaporated under reduced pressure. The residue was purified by flash column chromatography on silica gel (hexane/ethyl acetate) to afford the desired product.

Reference： [1]Tang, Jiansheng; Guo, Cancheng [Journal of Chemical Research, 2014, vol. 38, # 2, p. 123 - 127]

58
[ 17873-01-7 ]
[ 98-09-9 ]
[ 644-08-6 ]

Yield	Reaction Conditions	Operation in experiment
87%	With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tetrabutyl ammonium fluoride In N,N-dimethyl-formamide; acetonitrile at 100℃; for 3h; Inert atmosphere; Green chemistry;

Reference： [1]Zhang, Wei; Liu, Fang; Li, Ke; Zhao, Baoli [Applied Organometallic Chemistry, 2014, vol. 28, # 5, p. 379 - 381]

59
[ 570-02-5 ]
[ 17873-01-7 ]
[ 1040196-63-1 ]

Yield	Reaction Conditions	Operation in experiment
57%	With palladium(II) trifluoroacetate; C30H30N4; silver fluoride; In N,N-dimethyl acetamide; at 100℃; for 2h;	General procedure: To a mixture of aryl(trialkoxy)silane(0.20 mmol), AgF (76.6 mg, 0.60 mmol), Pd(TFA)2 (5.0 mg, 0.015 mmol,7.5 mol %), and ligand 1g (6.7 mg, 0.015 mmol, 7.5 mol %) in DMAc (1.0 mL)was added arylcarboxylic acid (0.40 mmol) at room temperature under an atmosphere of air. After the mixture was stirred at 100?or 110?C for 2-8 h, the mixture was diluted with ethyl acetate and water. The organic layer was washed with brine, dried over MgSO4, and concentrated under reduced pressure. The residue was purified by silica gel chromatography (hexane/EtOAc = 20:1).

Reference： [1]Tetrahedron Letters,2014,vol. 55,p. 3184 - 3188

60
[ 106-37-6 ]
[ 17873-01-7 ]
[ 97295-31-3 ]

Yield	Reaction Conditions	Operation in experiment
	With 2% active carbon-supported palladium; sodium hydroxide In water at 100℃;

Reference： [1]Mittapelly, Nagaraju; Mukkanti, Khagga; Reguri, Buchi Reddy [Asian Journal of Chemistry, 2014, vol. 26, # 4, p. 1015 - 1018]

61
[ 626-39-1 ]
[ 17873-01-7 ]
[ 50446-43-0 ]

Reference： [1]Asian Journal of Chemistry,2014,vol. 26,p. 1015 - 1018

62
S-methyl-S-(p-tolyl)sulfoximine [ No CAS ]
[ 17873-01-7 ]
N-(4-methylphenyl)-S,S-(4-methylphenyl)(methyl)sulfoximine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
79%	With copper(l) iodide; tetrabutyl ammonium fluoride; oxygen In dichloromethane at 20℃; for 12h; Schlenk technique; Green chemistry;

Reference： [1]Kim, Jaeeun; Ok, Jinpyo; Kim, Sanghyuck; Choi, Wonseok; Lee, Phil Ho [Organic Letters, 2014, vol. 16, # 17, p. 4602 - 4605]

63
[ 17873-01-7 ]
[ 77970-95-7 ]
(4-methoxyphenyl)(methyl)(p-tolylimino)-λ⁶-sulfanone [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
76%	With copper(l) iodide; tetrabutyl ammonium fluoride; oxygen In dichloromethane at 20℃; for 12h; Schlenk technique; Green chemistry;

Reference： [1]Kim, Jaeeun; Ok, Jinpyo; Kim, Sanghyuck; Choi, Wonseok; Lee, Phil Ho [Organic Letters, 2014, vol. 16, # 17, p. 4602 - 4605]

64
[ 22133-00-2 ]
[ 17873-01-7 ]
N-(4-methyl)phenyl-S-(3-chloro)phenyl-S-methylsulfoximine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
72%	With copper(l) iodide; tetrabutyl ammonium fluoride; oxygen In dichloromethane at 20℃; for 12h; Schlenk technique; Green chemistry;

Reference： [1]Kim, Jaeeun; Ok, Jinpyo; Kim, Sanghyuck; Choi, Wonseok; Lee, Phil Ho [Organic Letters, 2014, vol. 16, # 17, p. 4602 - 4605]

65
[ 17873-01-7 ]
[ 4381-25-3 ]
rac-N-[(4-methyl)-phenyl]-S-phenyl-S-methylsulfoximine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
78%	With copper(l) iodide; tetrabutyl ammonium fluoride; oxygen In dichloromethane at 20℃; for 12h; Schlenk technique; Green chemistry;

Reference： [1]Kim, Jaeeun; Ok, Jinpyo; Kim, Sanghyuck; Choi, Wonseok; Lee, Phil Ho [Organic Letters, 2014, vol. 16, # 17, p. 4602 - 4605]

66
C₁₁H₁₆FO₄P [ No CAS ]
[ 17873-01-7 ]
[ 1352918-73-0 ]

Yield	Reaction Conditions	Operation in experiment
94%	With 1,3-bis-(diphenylphosphino)propane; tetrabutyl ammonium fluoride; palladium diacetate In tetrahydrofuran; 1,4-dioxane at 100℃; for 24h; Schlenk technique; Inert atmosphere;	Hiyama Cross-Coupling; General Procedure: General procedure: An oven dried Schlenk tube with Pd(OAc)2 (5 mol%) and dppp (10 mol%) was evacuated and purged with argon three times. A mixture of TBAF (1 M in THF, 0.36 mL), 2a (0.45 mmol), and benzylic phosphate (1a; 0.30 mmol) was dissolved in freshly distilled 1,4-dioxane (1.0 mL), and added at r.t. The reaction mixture was heated with stirring at 100 °C for 24 h, then cooled to ambient temperature and transferred to around-bottom flask. Silica gel (2.0 g) was added and the solvent was removed under reduced pressure to afford a free flowing powder. The powder was then dry-loaded onto a silica gel column and purified by flash chromatography using petroleum as the eluent to give the desired product 3aa.

Reference： [1]Zhang, Pengbo; Xu, Jian; Gao, Yuzhen; Li, Xueqin; Tang, Guo; Zhao, Yufen [Synlett, 2014, vol. 25, # 20, p. 2928 - 2932]

67
[ 17873-01-7 ]
[ 128732-38-7 ]
1-(4-methylbenzyl)-3-(trifluoromethyl)benzene [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
86%	With 1,3-bis-(diphenylphosphino)propane; tetrabutyl ammonium fluoride; palladium diacetate In tetrahydrofuran; 1,4-dioxane at 100℃; for 24h; Schlenk technique; Inert atmosphere;	Hiyama Cross-Coupling; General Procedure: General procedure: An oven dried Schlenk tube with Pd(OAc)2 (5 mol%) and dppp (10 mol%) was evacuated and purged with argon three times. A mixture of TBAF (1 M in THF, 0.36 mL), 2a (0.45 mmol), and benzylic phosphate (1a; 0.30 mmol) was dissolved in freshly distilled 1,4-dioxane (1.0 mL), and added at r.t. The reaction mixture was heated with stirring at 100 °C for 24 h, then cooled to ambient temperature and transferred to around-bottom flask. Silica gel (2.0 g) was added and the solvent was removed under reduced pressure to afford a free flowing powder. The powder was then dry-loaded onto a silica gel column and purified by flash chromatography using petroleum as the eluent to give the desired product 3aa.

Reference： [1]Zhang, Pengbo; Xu, Jian; Gao, Yuzhen; Li, Xueqin; Tang, Guo; Zhao, Yufen [Synlett, 2014, vol. 25, # 20, p. 2928 - 2932]

68
[ 7145-06-4 ]
[ 17873-01-7 ]
[ 21895-16-9 ]

Yield	Reaction Conditions	Operation in experiment
95%	With 1,3-bis-(diphenylphosphino)propane; tetrabutyl ammonium fluoride; palladium diacetate In tetrahydrofuran; 1,4-dioxane at 100℃; for 24h; Schlenk technique; Inert atmosphere;	Hiyama Cross-Coupling; General Procedure: General procedure: An oven dried Schlenk tube with Pd(OAc)2 (5 mol%) and dppp (10 mol%) was evacuated and purged with argon three times. A mixture of TBAF (1 M in THF, 0.36 mL), 2a (0.45 mmol), and benzylic phosphate (1a; 0.30 mmol) was dissolved in freshly distilled 1,4-dioxane (1.0 mL), and added at r.t. The reaction mixture was heated with stirring at 100 °C for 24 h, then cooled to ambient temperature and transferred to around-bottom flask. Silica gel (2.0 g) was added and the solvent was removed under reduced pressure to afford a free flowing powder. The powder was then dry-loaded onto a silica gel column and purified by flash chromatography using petroleum as the eluent to give the desired product 3aa.

Reference： [1]Zhang, Pengbo; Xu, Jian; Gao, Yuzhen; Li, Xueqin; Tang, Guo; Zhao, Yufen [Synlett, 2014, vol. 25, # 20, p. 2928 - 2932]

69
[ 1428524-92-8 ]
[ 17873-01-7 ]
ethyl 2-(pyridin-3-yl)-2-(p-tolyl)acetate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
61%	With [Rh(OH)(cod)]2; tetrabutyl ammonium fluoride; tricyclohexylphosphine tetrafluoroborate In 1,4-dioxane; water at 100℃; for 5h; Inert atmosphere;

Reference： [1]Xia, Ying; Liu, Zhen; Feng, Sheng; Ye, Fei; Zhang, Yan; Wang, Jianbo [Organic Letters, 2015, vol. 17, # 4, p. 956 - 959]

70
[ 17873-01-7 ]
[ 72410-67-4 ]
tert-butyl 2-phenyl-2-(p-tolyl)acetate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
72%	With [Rh(OH)(cod)]2; tetrabutyl ammonium fluoride; tricyclohexylphosphine tetrafluoroborate In tetrahydrofuran; water at 80℃; for 5h; Inert atmosphere;

Reference： [1]Xia, Ying; Liu, Zhen; Feng, Sheng; Ye, Fei; Zhang, Yan; Wang, Jianbo [Organic Letters, 2015, vol. 17, # 4, p. 956 - 959]

71
[ 170891-76-6 ]
[ 17873-01-7 ]
2,2-dimethyl-N-(quinolin-8-yl)-3-(p-tolyloxy)propanamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
79%	With di-<i>tert</i>-butyl dicarbonate; copper diacetate; sodium pivalate; cesium fluoride; silver(l) oxide In N,N-dimethyl-formamide at 150℃; for 0.5h; Sealed tube; Inert atmosphere; regioselective reaction;

Reference： [1]Zhang, Jitan; Chen, Hui; Wang, Binjie; Liu, Zhanxiang; Zhang, Yuhong [Organic Letters, 2015, vol. 17, # 11, p. 2768 - 2771]

72
[ 17873-01-7 ]
[ 15163-59-4 ]
[ 70680-21-6 ]

Yield	Reaction Conditions	Operation in experiment
93%	With copper (II)-fluoride; [Pd(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)(naphthoquinone)]₂; silver carbonate In N,N-dimethyl acetamide at 130℃; for 19h; Inert atmosphere; Sealed tube; Glovebox;

Reference： [1]Katayev, Dmitry; Exner, Benjamin; Goossen, Lukas J. [ChemCatChem, 2015, vol. 7, # 14, p. 2028 - 2032]

73
[ 591-50-4 ]
[ 17873-01-7 ]
[ 644-08-6 ]

Yield	Reaction Conditions	Operation in experiment
83%	With potassium fluoride; tetra-(n-butyl)ammonium iodide In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere;	General Procedure for Hiyama Cross-Coupling Reactions. General procedure: A typical procedure for the cross-coupling reaction using the nanocrystals is as follows: degassed N,N'-dimethylacetamide (DMA) (1.0 mL), aryl halide (0.5 mmol), trimethoxyphenylsilane (1.5 mmol), KF (1.5 mmol), tetrabutylammonium iodide (TBAI) (0.1 mmol), and Pd-Fe3O4 catalyst (1 mol%) were added to a vial, which was equipped with a magnetic bar and purged with argon gas. The vial was sealed and the reaction mixture was heated to 150 °C for 16 h with vigorous stirring. After the reaction, the mixture was cooled to room temperature and the catalyst was collected using an external magnet. The solution containing products was diluted and extracted between dichloromethane (10 mL) and H2O(10 mL). The organic layer was dried over MgSO4, filtered, and concentrated under reduced pressure. The residue was purified by silica-gel column chromatography using a 1:6 mixture of ethyl acetate and n-hexane as an eluent to furnish the desired products.

Reference： [1]Lee, Woong-Sup; Byun, Sangmoon; Kwon, Jungmin; Kim, B. Moon [Bulletin of the Korean Chemical Society, 2016, vol. 37, # 12, p. 1992 - 1997]

74
[ 3389-54-6 ]
[ 17873-01-7 ]
(4'-methyl-[1,1'-biphenyl]-2-yl)(pyrrolidin-1-yl)methanone [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
89%	With copper (II)-fluoride; silver hexafluoroantimonate; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂ In tetrahydrofuran at 140℃; for 20h;

Reference： [1]Nareddy, Pradeep; Jordan, Frank; Szostak, Michal [Chemical Science, 2017, vol. 8, # 4, p. 3204 - 3210]

75
[ 221044-05-9 ]
[ 17873-01-7 ]
[ 1608124-60-2 ]

Yield	Reaction Conditions	Operation in experiment
87%	With copper (II)-fluoride; silver hexafluoroantimonate; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂ In water at 140℃; for 20h; Inert atmosphere; Green chemistry;
71%	With copper (II)-fluoride; oxygen; cobalt(III) acetylacetonate In toluene at 160℃; for 24h; Sealed tube;

Reference： [1]Nareddy, Pradeep; Jordan, Frank; Szostak, Michal [Organic Letters, 2018, vol. 20, # 2, p. 341 - 344]
[2]Lu, Ming-Zhu; Ding, Xin; Shao, Changdong; Hu, Zhengsong; Luo, Haiqing; Zhi, Sanjun; Hu, Huayou; Kan, Yuhe; Loh, Teck-Peng [Organic Letters, 2020, vol. 22, # 7, p. 2663 - 2668]

76
[ 17873-01-7 ]
diethyl 2,2′-disulfanediylbis(6-methyl-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate) [ No CAS ]
[ 1048007-29-9 ]

Yield	Reaction Conditions	Operation in experiment
70%	With copper(I) thiophene-2-carboxylate; tetrabutyl ammonium fluoride; palladium diacetate; tricyclohexylphosphine In tetrahydrofuran at 60℃; for 24h; Sealed tube; Schlenk technique; Inert atmosphere;	2.2 General Procedure for synthesis 3a-6c. General procedure: Disulfide 1a (0.2 mmol, 0.1094 g), Pd(OAc)2 (3 mol %), CuTC (3.0 equiv), PCy3 (6 mol %), was added respectively to the sealed Schlenktube, Then phenyltrimethoxysilane 2a (3.0 equiv, 0.6 mmol, 0.1188 g), TBAF (3.0 equiv, 0.6 mmol) and solvent THF (2 mL) was injectedinto the sealed tube by syringe in the presence of nitrogen. The mixture was stirred at 60 °C for 24 h. And the progress of the reaction wasmonitored by thin-layer chromatography (silica gel). After completion of the reaction, mixture was cooled to ambient temperature,quenched by addition of saturated NH4Cl (2 mL), and extracted with ethyl acetate (3×10 mL). The organic layers were combined and driedwith anhydrous MgSO4 and concentrated in vacuo, the resulting residue was purified by silica gel column chromatography using ethylacetate/petroleum ether (1:50) as eluent to afford the products (3a-6c).

Reference： [1]Liu, Ming-Xia; Gong, Hai-Peng; Quan, Zheng-Jun; Wang, Xi-Cun [Synlett, 2018, vol. 29, # 3, p. 330 - 335]

77
[ 67-56-1 ]
[ 931-70-4 ]
[ 17873-01-7 ]

Yield	Reaction Conditions	Operation in experiment
93%	With graphene immobilized iridium complex containing N-heterocyclic carbene ligand functionalized with pyrene at 30℃; for 0.333333h;

Reference： [1]Ventura-Espinosa, David; Sabater, Sara; Carretero-Cerdán, Alba; Baya, Miguel; Mata, Jose A. [ACS Catalysis, 2018, vol. 8, # 3, p. 2558 - 2566]

78
[ 7188-38-7 ]
[ 17873-01-7 ]
[ 62-53-3 ]
N-(tert-butyl)-4-methyl-N'-phenylbenzimidamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
67%	With potassium fluoride; copper diacetate; palladium dichloride In N,N-dimethyl-formamide at 120℃; for 24h;

Reference： [1]Zhu, Fengxiang; Wu, Xiao-Feng [New Journal of Chemistry, 2018, vol. 42, # 12, p. 10396 - 10399]

79
[ 201230-82-2 ]
[ 17873-01-7 ]
[ 62-53-3 ]
[ 6833-18-7 ]

Yield	Reaction Conditions	Operation in experiment
88%	With copper (II)-fluoride; bis(triphenylphosphine)palladium(II) dichloride In acetonitrile at 80℃; for 24h; Schlenk technique;
88%	With copper (II)-fluoride; bis-triphenylphosphine-palladium(II) chloride In acetonitrile at 80℃; for 24h; Sealed tube;	10 Preparation of 4-methyl-N-phenylbenzamide 0.75 mmol of p-methyl(trimethoxy)phenylsilane 10 mol% Pd(PPh3)Cl2 and 2equiv.CuF2 were dissolved in 3 mL CH3CN Shrek tube (with magnetic stirrer), and the reaction tube was closed from the reaction tube. The branch pipe is filled with carbon monoxide, filled with balloons and then emptied, three times, until the air is completely emptied, then the balloon is filled, then 0.5 mmol of aniline was added to the reaction tube, and the mixture was stirred under heating at 80 ° C for 24 hours. The reaction was monitored by TLC. After the reaction was completed, the mixture was extracted three times with 10 mL of ethyl acetate. 92.8 mg of a white solid compound was obtained in a yield of 88%.

Reference： [1]Zhang, Jin; Hou, Yanyan; Ma, Yangmin; Szostak, Michal [Journal of Organic Chemistry, 2019, vol. 84, # 1, p. 338 - 345]
[2]Current Patent Assignee: SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY - CN109180518, 2019, A Location in patent: Paragraph 0121; 0122; 0123; 0124

80
[ 1182669-71-1 ]
[ 17873-01-7 ]
4′-methyl-3-methyl-N-(quinolin-8-yl)-[1,1′-biphenyl]-2-carboxamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
66%	With copper (II)-fluoride; cobalt(II) acetate; cesium fluoride In 1-methyl-pyrrolidin-2-one at 100℃; for 20h; Schlenk technique; Inert atmosphere;

Reference： [1]Bu, Qingqing; Gońka, Elżbieta; Kuciński, Krzysztof; Ackermann, Lutz [Chemistry - A European Journal, 2019, vol. 25, # 9, p. 2213 - 2216]

81
[ 33757-48-1 ]
[ 17873-01-7 ]
4'-methyl-N-(quinolin-8-yl)-[1,1'-biphenyl]-2-carboxamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
63%	With copper (II)-fluoride; cobalt(II) acetate; cesium fluoride In 1-methyl-pyrrolidin-2-one at 100℃; for 20h; Schlenk technique; Inert atmosphere;

Reference： [1]Bu, Qingqing; Gońka, Elżbieta; Kuciński, Krzysztof; Ackermann, Lutz [Chemistry - A European Journal, 2019, vol. 25, # 9, p. 2213 - 2216]

82
[ 17873-01-7 ]
(1-fluoro-2,2-diiodovinyl)benzene [ No CAS ]
(Z)-1-(2-fluoro-2-phenylethenyl)-4-methylbenzene [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
73%	With 1,4-diaza-bicyclo[2.2.2]octane; tetrabutyl ammonium fluoride; palladium diacetate In tetrahydrofuran; 1,4-dioxane at 80℃; for 20h; regioselective reaction;

Reference： [1]Jayaraman, Aravindan; Lee, Sunwoo [Organic Letters, 2019, vol. 21, # 10, p. 3485 - 3489]

83
[ 2441-97-6 ]
[ 17873-01-7 ]
(–)-(S)-3-(4-methylphenyl)cyclohexene [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
53%	With bis(acetonitrile)(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; tetrabutyl ammonium fluoride; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine) In tetrahydrofuran for 3h; Reflux; enantioselective reaction;

Reference： [1]González, Jesús; Schäfer, Philipp; Fletcher, Stephen P. [Organometallics, 2019, vol. 38, # 20, p. 3991 - 3995]

84
[ 17873-01-7 ]
N-tert-butoxycarbonyl-5-chloro-3-piperidene [ No CAS ]
(–)-tert-butyl (S)-3-(p-tolyl)-3,6-dihydropyridine-1(2H)-carboxylate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
40%	With bis(acetonitrile)(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; tetrabutyl ammonium fluoride; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine) In tetrahydrofuran for 3h; Reflux; enantioselective reaction;

Reference： [1]González, Jesús; Schäfer, Philipp; Fletcher, Stephen P. [Organometallics, 2019, vol. 38, # 20, p. 3991 - 3995]

85
[ 1506-76-9 ]
[ 17873-01-7 ]
[ 121-44-8 ]
C₁₂₆H₉₀O₂₄Si₆^(6-)*6C₆H₁₅N*6H⁽¹⁺⁾ [ No CAS ]

Reference： [1]Chemical Communications,2019,vol. 55,p. 6066 - 6069

86
[ 17873-01-7 ]
N,N,N-trimethyl-1-(4-cyanophenyl)methanaminium trifluoromethanesulfonate [ No CAS ]
[ 71947-05-2 ]

Yield	Reaction Conditions	Operation in experiment
97%	With dichloro bis(acetonitrile) palladium(II); tetrabutyl ammonium fluoride; cyclohexyldiphenylphosphine In ethanol at 120℃; for 24h; Inert atmosphere; Schlenk technique;

Reference： [1]Han, Chunyu; Zhang, Zhenming; Xu, Silin; Wang, Kai; Chen, Kaiting; Zhao, Junfeng [Journal of Organic Chemistry, 2019, vol. 84, # 24, p. 16308 - 16313]

87
[ 573-57-9 ]
[ 17873-01-7 ]
[ 1505513-83-6 ]
(1R,2S)-2-(4-methylphenyl)-1,2-dihydronaphthalen-1-ol [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
83 % ee	With (S)-((4,4’-bi-1,3-benzodioxole)-5,5’-diyl)bis(diphenylphosphine); tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; CuF₂*H₂O In water; 1,2-dichloro-ethane at 20℃; Overall yield = 89 percent; Overall yield = 42.1 mg; enantioselective reaction;

Reference： [1]Tan, Yun; Yao, Yongqi; Yang, Wen; Lin, Qifu; Huang, Guobao; Tan, Minxiong; Chen, Shuqi; Chen, Donghan; Yang, Dingqiao [Advanced Synthesis and Catalysis, 2020, vol. 362, # 1, p. 139 - 145]

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CAS No. :	17873-01-7	MDL No. :	MFCD00048020
Formula :	C₁₀H₁₆O₃Si	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	XQEGZYAXBCFSBS-UHFFFAOYSA-N
M.W :	212.32	Pubchem ID :	2760672
Synonyms :

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313	UN#:	N/A
Hazard Statements:	H315-H319	Packing Group:	N/A
GHS Pictogram:

Precautionary Statements-General
Code	Phrase
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Prevention
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P285	In case of inadequate ventilation wear respiratory protection.
P231 + P232	Handle under inert gas. Protect from moisture.
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Response
Code	Phrase
P301	IF SWALLOWED:
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P320
P302 + P352	IF ON SKIN: wash with plenty of soap and water.
P321
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P336	Thaw frosted parts with lukewarm water. Do not rub affected area.
P337	If eye irritation persists:
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P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
P351	Rinse cautiously with water for several minutes.
P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
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P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
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P401
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H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 17873-01-7 ] {[proInfo.proName]}

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[ 17873-01-7 ] Synthesis Path-Downstream 1~87

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