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Chemical Structure| 1795-31-9 Chemical Structure| 1795-31-9

Structure of 1795-31-9

Chemical Structure| 1795-31-9

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Product Details of [ 1795-31-9 ]

CAS No. :1795-31-9
Formula : C9H27O3PSi3
M.W : 298.54
SMILES Code : C[Si](OP(O[Si](C)(C)C)O[Si](C)(C)C)(C)C
MDL No. :MFCD00015588
InChI Key :VMZOBROUFBEGAR-UHFFFAOYSA-N
Pubchem ID :137213

Safety of [ 1795-31-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P305+P351+P338

Application In Synthesis of [ 1795-31-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1795-31-9 ]

[ 1795-31-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 2491-15-8 ]
  • [ 1795-31-9 ]
  • trimethylsilyl N-formylglycinate [ No CAS ]
  • 2
  • [ 2491-15-8 ]
  • [ 27607-77-8 ]
  • [ 1795-31-9 ]
  • [ 3663-52-3 ]
  • trimethylsilyl N-{bis[bis(trimethylsiloxy)phosphoryl]methyl}glycinate [ No CAS ]
YieldReaction ConditionsOperation in experiment
92% In dichloromethane; at 20℃; for 2h;Inert atmosphere; a. Trimethylsilyl trifluoromethanesulfonate (0.004 mol, 0.89 g),was added under stirring to a mixture of tris(trimethylsilyl) phosphite(0.079 mol, 23.5 g) and N-<strong>[2491-15-8]formylglycine</strong> 1a (0.0175 mol, 1.8 g)in methylene chloride (10 mL). The mixture was kept at 20 C for 2 h. The solvent was removed and then an excess of tris(-trimethylsilyl) phosphite and bis(trimethylsilyl) phosphite weredistilled off under vacuum of 0.5mm Hg to obtain 9.8 g ofdiphosphonate 3a, yield 92%, thick oil. 1H NMR (400 MHz, CDCl3), delta,ppm: -0.36 s (Me3Si), -0.32 s (4 Me3Si), 2.54 t (C1H, 2JPH 20.8 Hz),3.11 s (C2H2). 13C NMR (100 MHz, CDCl3), delta, ppm: -1.7 s (Me3Si),-0.3 s (4 Me3Si), 49.7 t (C2, 3JPC 7.2 Hz), 53.7 t (C1, 1JPC 152.3 Hz),169.9 s (CO). 31P NMR (162 MHz, CDCl3), d, ppm: 0.7 s. According tothe 31P NMR spectrum, the substance contains bis(trimethylsilyl)phosphite, d, ppm: -13.9 s (3 mol. %). It should be noted that thisimpurity was converted to phosphorous acid and removed duringthe synthesis of the corresponding acid 4a (cf. in Ref. [13]).
 

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