Home Cart Sign in  
Chemical Structure| 18096-70-3 Chemical Structure| 18096-70-3

Structure of 18096-70-3

Chemical Structure| 18096-70-3

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 18096-70-3 ]

CAS No. :18096-70-3
Formula : C12H15NO2
M.W : 205.25
SMILES Code : O=C(C1=CC=C(OC)C=C1)/C=C/N(C)C
MDL No. :MFCD00097914

Safety of [ 18096-70-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Application In Synthesis of [ 18096-70-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 18096-70-3 ]

[ 18096-70-3 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 28710-97-6 ]
  • [ 18096-70-3 ]
  • [ 1081141-61-8 ]
  • 2
  • [ 391-12-8 ]
  • [ 18096-70-3 ]
  • (2-oxo-7-(trifluoromethyl)-1’H-spiro[indoline-3,4’-pyridine]-3’,5’-diyl)bis[(4-methoxyphenyl)methanone] [ No CAS ]
YieldReaction ConditionsOperation in experiment
64% With ammonium acetate; acetic acid; In ethanol; water; at 80℃; for 6h;Green chemistry; General procedure: With a mixture of N,N-Dimethylenaminones 1 (1.0 mmol), isatins 2 (0.5 mmol), ammonium acetate 3 (1.0 mmol) in AcOH (1 mL) and EtOH?water (1:4) (5 mL), the reaction mixture was stirred at 80 °C for 6 h until TLC indicated that the reaction was completed. The reaction mixture was allowed to cool to room temperature, neutralised with a saturated solution of Na2CO3 to pH 8?9, and then was extracted with ethyl acetate (2 × 30 mL). The organic phase was washed with water (20 mL) and the organic layer dried over Na2SO4, and concentrated under reduced pressure. The crude product was chromatographed onsilica gel (200?300 mesh) using a mixture of petroleum ether and ethyl acetate as eluent to afford the product 4.
  • 3
  • [ 580-15-4 ]
  • [ 18096-70-3 ]
  • 1-(4-methoxyphenyl)-3-(quinolin-6-ylamino)prop-2-en-1-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
86% With potassium hydrogensulfate; In ethanol; water; at 20℃; for 0.166667h;Sonication; General procedure: To a mixture of 3-aminoquinoline (1 mmol) and enaminones4a (1 mmol) in 6 cm3of EtOH: H2O(1:1) taken in a roundbottomflask was added KHSO4(2 mmol) and the resultingmixture was irradiated in an ultrasound cleaner for 10 minat room temperature when a solid product precipitated out.The progress and completion of the reaction was monitoredby TLC. The precipitate was collected by filtration withrepeated washing with water to ensure complete removal ofthe acid and then dried to give a practically pure 5a in 89%yield. Further purification of 5a was carried out by silicagel column chromatography using 50% EtOAc-hexane.The rest of the enaminones 5b-5e, 6a-6e, and 7a-7e wereequally easily prepared in 10-12 min in 79-94% overallyields. The structures of these enaminones were unambiguouslyassigned with the help of analytical and spectral datapresented hereunder.
 

Historical Records

Technical Information

Categories