Home Cart Sign in  
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 18312-46-4 Chemical Structure| 18312-46-4

Structure of 18312-46-4

Chemical Structure| 18312-46-4

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 18312-46-4 ]

CAS No. :18312-46-4
Formula : C7H10N2O
M.W : 138.17
SMILES Code : NNC1=CC=CC=C1OC
MDL No. :MFCD00460677

Safety of [ 18312-46-4 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H315-H318-H335
Precautionary Statements:P261-P280-P301+P310-P305+P351+P338
Class:8(6.1)
UN#:2923
Packing Group:

Application In Synthesis of [ 18312-46-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 18312-46-4 ]

[ 18312-46-4 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 146137-79-3 ]
  • [ 18312-46-4 ]
  • C15H12FN3O [ No CAS ]
  • 2
  • [ 21168-41-2 ]
  • [ 18312-46-4 ]
  • 8-chloro-2-(2-methoxyphenyl)-2H,3H,5H-pyrazolo[4,3-c]quinolin-3-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
28% With triethylamine; In N,N-dimethyl acetamide; at 140℃; for 16h; In an 8 mL-vial with magnetic stirrer and screw cap, ethyl 4,6-dichloroquinoline- 3-carboxylate (135 mg, 0.5 mmol, 1 equiv), 2-methoxyphenylhydrazine (83 mg, 0.6 mmol, 1.2 equiv) and triethylamine (63 mg, 0.6 mmol, 1.2 equiv) were dissolved in dry N,N- dimethylacetamide (3 mL). The reaction mixture was heated to 140 C for 16 hours. After completion of the reaction the reaction mixture was evaporated to dryness. The crude product was purified by flash-column chromatography (45 g silica 60, eluent EtOAc/MeOH 5%) Co-eluting triethylamine hydrochloride was subsequently removed by washing with water. Yield: 28% (0.14 mmol, 46 mg) (28%). Appearance: yellow solid. TLC: 0.07 (EtOAc/MeOH 10%). M.p.310 - 313 C with partial decomposition.1H-NMR (200 MHz, DMSO-d6) delta = 3.73 (s, 3H), 7.03 (t, J = 7.5 Hz, 1H), 7.16 (d, J = 8.2 Hz, 1H), 7.29-7.45 (m, 2H), 7.62-7.73 (m, 2H), 8.01 (d, J = 1.6 Hz, 1H), 8.65 (s, 1H), 12.78 (s, 1H).13C-NMR (50 MHz, DMSO-d6) delta = 55.6 (q), 105.3 (s), 112.5 (d), 120.2 (d), 120.3 (s), 120.9 (d), 121.4 (d), 127.7 (s), 129.3 (d), 129.4 (d), 129.7 (d), 130.3 (s), 134.0 (s), 139.1 (d), 141.4 (s), 155.1 (s), 161.6 (s). HR-ESI-MS: m/z 326.0678 [M+H]+ (calcd 326.0691, diff- 3.99 ppm)
 

Historical Records

Technical Information

Categories