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Chemical Structure| 1844-53-7 Chemical Structure| 1844-53-7

Structure of 1844-53-7

Chemical Structure| 1844-53-7

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Product Details of [ 1844-53-7 ]

CAS No. :1844-53-7
Formula : C12H8ClN3
M.W : 229.67
SMILES Code : ClC1=NN2C(C=C1)=NC(C3=CC=CC=C3)=C2
MDL No. :MFCD03407868

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Application In Synthesis of [ 1844-53-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1844-53-7 ]

[ 1844-53-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 625-51-4 ]
  • [ 1844-53-7 ]
  • 3-acetamidomethyl-6-chloro-2-phenylimidazo<1,2-b>pyridazine [ No CAS ]
  • 2
  • [ 952514-79-3 ]
  • [ 1844-53-7 ]
  • C31H21N5 [ No CAS ]
YieldReaction ConditionsOperation in experiment
83% With tetrakis(triphenylphosphine) palladium(0); potassium carbonate; In tetrahydrofuran; for 10h;Reflux; Inert atmosphere; In a flask, Intermediate 1-1 (1 g, 4.4 mmol) was added,B-[4-(1-phenyl-1H-benzimidazol-2-yl)phenyl]-boronic acid (1.4 g, 4.4 mmol),Tetratriphenylphosphine palladium (0.1 g), potassium carbonate (1.4 g, 10 mmol),Tetrahydrofuran (15 mL), water (10 mL) and heated under reflux for 10 hours under nitrogenCool, extract with dichloromethane, dry, concentrate,Purification by column chromatography gave a product of 1.7 g with a yield of 83%.
 

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