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Chemical Structure| 187032-53-7 Chemical Structure| 187032-53-7

Structure of 187032-53-7

Chemical Structure| 187032-53-7

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Product Details of [ 187032-53-7 ]

CAS No. :187032-53-7
Formula : C11H11NO4
M.W : 221.21
SMILES Code : O=C([C@@H](O)[C@@H]1O)N(CC2=CC=CC=C2)C1=O
MDL No. :MFCD04972319

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Application In Synthesis of [ 187032-53-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 187032-53-7 ]

[ 187032-53-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 187032-53-7 ]
  • [ 90365-74-5 ]
YieldReaction ConditionsOperation in experiment
86.59% With borane-THF; In tetrahydrofuran; at 70℃; for 3h; General procedure: Borane in THF (1.0 M) (17.19 mL, 180.99 mmol) was added drop-wise to a solution of 2a (10.0 g, 45.24 mmol) in THF (200 mL) at RT, after completion of addition, reaction mixture was slowly heated to 70 °C for 3 h. The reaction mixture was cooled to 0 °C, quenched with methanol (50 mL) by the drop-wise addition, slowly warmed to RT, stirred for 1 h. (Note: intensive gas evolution is occurred). The reaction mixture was concentrated in vacuo, crude was purified on a silica gel column using a linear gradient of ethyl acetate in Pet-ether yielding 7.73 g (88.5percent) of yellowish crystals of compound 3a.
 

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