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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
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Chemical Structure| 18879-80-6 Chemical Structure| 18879-80-6

Structure of 18879-80-6

Chemical Structure| 18879-80-6

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Product Details of [ 18879-80-6 ]

CAS No. :18879-80-6
Formula : C7H7IN2S
M.W : 278.11
SMILES Code : S=C(N)NC1=CC=C(I)C=C1
MDL No. :MFCD00041183

Safety of [ 18879-80-6 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301
Precautionary Statements:P501-P270-P264-P301+P310+P330-P405
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 18879-80-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 18879-80-6 ]
  • Downstream synthetic route of [ 18879-80-6 ]

[ 18879-80-6 ] Synthesis Path-Upstream   1~2

  • 1
  • [ 18879-80-6 ]
  • [ 16582-58-4 ]
YieldReaction ConditionsOperation in experiment
73% With bromine In chloroform for 6 h; Reflux (0143) Chloroform suspension (7 ml) of 1-(4-iodophenyl)thiourea (889 mg, 3.19 mmol) was added with bromine (328 μl, 6.40 mmol), and heated to reflux and stirred for 6 hours. After the reaction was completed and the solvent was removed, the residue was added with dichloromethane and washed with saturated sodium bicarbonate solution and saturated sodium chloride solution. After the solution was dried over anhydrous sodium sulfate and the solvent was removed under reduced pressure, the resulting deposits were filtered to obtain 650 mg 2-amino-6-iodobenzothiazole in a yield of 73percent.
References: [1] Patent: US2016/2600, 2016, A1, . Location in patent: Paragraph 0143.
[2] Recueil des Travaux Chimiques des Pays-Bas, 1935, vol. 54, p. 122,127.
[3] Journal of the Indian Chemical Society, 1931, vol. 8, p. 147,163.
[4] Journal of Medicinal Chemistry, 1999, vol. 42, # 15, p. 2828 - 2843.
  • 2
  • [ 67-66-3 ]
  • [ 18879-80-6 ]
  • [ 7726-95-6 ]
  • [ 16582-58-4 ]
References: [1] Recueil des Travaux Chimiques des Pays-Bas, 1935, vol. 54, p. 122,127.
[2] Journal of the Indian Chemical Society, 1931, vol. 8, p. 147,163.
 

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