Home Cart Sign in  
Chemical Structure| 191731-32-5 Chemical Structure| 191731-32-5

Structure of 191731-32-5

Chemical Structure| 191731-32-5

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 191731-32-5 ]

CAS No. :191731-32-5
Formula : C12H17NO4
M.W : 239.27
SMILES Code : O=C(N(OC)C)COCC1=CC=C(OC)C=C1

Safety of [ 191731-32-5 ]

Application In Synthesis of [ 191731-32-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 191731-32-5 ]

[ 191731-32-5 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 67442-07-3 ]
  • [ 105-13-5 ]
  • 2-(4-Methoxy-benzyloxy)-N-methyl-acetamide [ No CAS ]
  • [ 191731-32-5 ]
  • 2
  • [ 67442-07-3 ]
  • [ 105-13-5 ]
  • [ 191731-32-5 ]
YieldReaction ConditionsOperation in experiment
9.85% In tetrahydrofuran; ethyl acetate; Step 1. N-methoxy-2-((4-methoxybenzyl)oxy)-N-methylacetamide To a suspension of sodium hydride (1.86 g, 46.5 mmol) in THF (80 ml) at 0° C. was added (4-methoxyphenyl)methyl alcohol (5.80 mL, 46.7 mmol) over 5 min. The reaction mixture was warmed to RT for 1 h, then cooled to 0° C. and a solution of <strong>[67442-07-3]2-chloro-N-methoxy-N-methylacetamide</strong> (6.50 g, 47.3 mmol) in THF (20 mL) was added. The reaction mixture was warmed to room temperature and stirred for 72 hr then quenched with NH4Cl and diluted with EtOAc and water. The aqueous phase was extracted with EtOAc (2*) and the combined organic extracts were washed with brine (1*), dried over MgSO4, filtered, and concentrated. Purification by flash column chromatography on silica gel (120 g, 30percent to 80percent EtOAc in hexanes) gave N-methoxy-2-((4-methoxybenzyl)oxy)-N-methylacetamide (1.10 g, 4.60 mmol, 9.85percent yield) as a yellow oil. ESI (M+Na) 262.1.
 

Historical Records

Technical Information

Categories