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Chemical Structure| 192323-07-2 Chemical Structure| 192323-07-2

Structure of 192323-07-2

Chemical Structure| 192323-07-2

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Product Details of [ 192323-07-2 ]

CAS No. :192323-07-2
Formula : C12H24N2O2
M.W : 228.33
SMILES Code : O=C(OC(C)(C)C)NC[C@H]1CC[C@H](N)CC1
MDL No. :MFCD06657670
InChI Key :HMMYZMWDTDJTRR-UHFFFAOYSA-N
Pubchem ID :21882540

Safety of [ 192323-07-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 192323-07-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 192323-07-2 ]

[ 192323-07-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 21168-41-2 ]
  • [ 192323-07-2 ]
  • ethyl 4-((trans-4-(((tert-butoxycarbonyl)amino)methyl)cyclohexyl)amino)-6-chloroquinoline-3-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
With N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; at 90℃; Example 5 tert-butyl ((trans-4-((6-chloro-3-(hydroxymethyl)quinolin-4-yl)amino)cyclohexyl)methyl)-carbamate (3b). In a stirring 1,4-dioxane solution (8 ml) of <strong>[21168-41-2]ethyl 4,6-dichloroquinoline-3-carboxylate</strong> (1 equiv., 1.0 mmol), tert-butyl ((trans-4-aminocyclohexyl)methyl)carbamate (1 equiv., 1.0 mmol) and N,N-diisopropylethylamine (3 equiv., 3.0 mmol) were added and allowed to dissolve. The resulting solution was heated up to 90 C., and overnight before cooling to room temperature. The solvent was removed under reduced pressure to afford the crude product ethyl 4-((trans-4-(((tert-butoxycarbonyl)amino)methyl)cyclohexyl)amino)-6-chloroquinoline-3-carboxylate (3a), which was used for the next step without purification. MS (ESI) calculated for C24H33ClN3O4 [M+H]+, 462; found 462.
 

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