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Chemical Structure| 197073-43-1 Chemical Structure| 197073-43-1

Structure of 197073-43-1

Chemical Structure| 197073-43-1

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Product Details of [ 197073-43-1 ]

CAS No. :197073-43-1
Formula : C14H17NO4
M.W : 263.29
SMILES Code : O=C(O)/C=C/C1=CC=C(NC(OC(C)(C)C)=O)C=C1
MDL No. :MFCD02682305

Safety of [ 197073-43-1 ]

Application In Synthesis of [ 197073-43-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 197073-43-1 ]

[ 197073-43-1 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 29390-67-8 ]
  • [ 197073-43-1 ]
  • C56H86N2O37 [ No CAS ]
  • 2
  • [ 79-10-7 ]
  • [ 6163-58-2 ]
  • [ 131818-17-2 ]
  • [ 197073-43-1 ]
YieldReaction ConditionsOperation in experiment
With triethylamine;palladium(II) chloride; In dichloromethane; water; To a mixture of 27 g of 4-(t-butoxycarbonylamino)-bromobenzene, 0.18 g of palladium chloride, 1.25 g of tri-O-tolylphosphine and 50 ml of triethylamine is added 9.5 ml of acrylic acid followed by 25 ml of triethylamine. The reaction mixture is heated under reflux for 3 hours. Methylene chloride (250 ml) is added, the reaction mixture is filtered and evaporated to dryness. The residue is suspended in water, the suspension is washed with toluene, concentrated HCl is added while cooling to pH5. The resulting 4-(t-butoxycarbonylamino)-cinnamic acid is collected, washed with water and dried; m.p. 175-177.
 

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